Falciparum Malaria
Scientists at University of Cape Town discuss research in falciparum malaria in children
Published in Malaria Weekly, January 15th, 2007
Research findings, "Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications," are discussed in a new report. According to a study from Cape Town, South Africa, "Our objective was to characterize the pharmacokinetic properties of sulfadoxine-pyrimethamine in African adults and children with acute falciparum malaria. Despite decades of widespread use, there are few data to inform dose recommendations."
"In a prospective multicenter pharmacokinetic study in 307 patients with acute falciparum malaria, capillary blood concentrations of sulfadoxine and pyrimethamine were determined at 9 visits over a period of 42 days by mass spectrometry. After...
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Source: Malaria Weekly (2007-01-15)
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