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Hookworm Disease
Findings from R.T. Fujiwara and co-authors broaden understanding of hookworm disease
June 15th, 2009
"Hookworms survive for several years (5 to 7 years) in the host lumen, inducing a robust but largely ineffective immune response. Among the most striking aspects of the immune response to hookworm (as with many other helminths) is the ablation of parasite-specific T cell proliferative response (hyporesponsiveness)," researchers in Belo Horizonte, Brazil report. "While the role of the adaptive immune response in human helminth infection has been well investigated, the role of the innate immune responses (e. g., dendritic cells and eosinophils) has received less attention and remains to be clearly elucidated. We report on the differentiation/maturation of host dendritic...
Source: Malaria Weekly (2009-06-15)
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