Falciparum Malaria
New falciparum malaria research from B.N. Acharya and co-researchers described
Published in Malaria Weekly, April 12th, 2010
According to a study from Gwalior, India, "A series of 1,3,5-trisubstituted pyrazolines were synthesized and evaluated for in vitro antimalarial efficacy against chloroquine sensitive (MRC-02) as well as chloroquine resistant (RKL9) strains of Plasmodium falciparum. The activity was at nano molar concentration. beta-hematin formation inhibition activity (BHIA(50)) of the pyrazolines were determined and correlated with antimalarial activity."
"A reasonably good correlation (r = 0.62) was observed between antimalarial activity (IC50) and BHIA(50). This suggests that antimalarial mode of action of this class of compounds appears to be similar to that of chloroquine and...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Malaria Weekly
Source: Malaria Weekly (2010-04-12)
More Articles from Malaria Weekly
- University of Dundee
Drug breakthrough in fight against neglected diseases - University of Utah Health Sciences
Researchers identify potential new target for treating hepatitis C - Anemia
New anemia findings from University of Michigan described - Falciparum Malaria
Findings from Y. Kabri et al in falciparum malaria reported - Falciparum Malaria
Research conducted by V. Tomar and co-researchers has updated our knowledge about falciparum malaria - Falciparum Malaria
Researchers from Thammasat University describe findings in falciparum malaria - More from this issue of Malaria Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
