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Falciparum Malaria

Findings from University of Cambridge, Department of Biochemistry in falciparum malaria reported

Published in Malaria Weekly, April 19th, 2010

Research findings, 'Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion-blocking antibodies,' are discussed in a new report. According to recent research published in the journal JMB Online, "Plasmodium falciparum malaria remains one of the world's leading causes of human suffering and poverty. Each year, the disease takes 1-3 million lives, mainly in sub-Saharan Africa."

"The adhesion of infected erythrocytes (IEs) to vascular endothelium or placenta is the key event in the pathogenesis of severe P. falciparum infection. In pregnant women, the parasites express a single and unique...

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