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African Trypanosomiasis

Scientists at Dupuytren University publish new data on African trypanosomiasis

Published in Malaria Weekly, April 26th, 2010

According to recent research from Limoges, France, "In human African trypanosomiasis (HAT, sleeping sickness), staging of disease and treatment follow-up relies on white cell count in the cerebrospinal fluid (CSF). As B lymphocytes (CD19 positive cells) are not found in the CSF of healthy individuals but occur in neurological disorders such as multiple sclerosis, B lymphocyte count may be useful for field diagnosis/staging and therapeutic follow-up in HAT."

"Seventy-one HAT patients were diagnosed and 50 were followed-up 6-24 months after treatment. White cell counts were used for conventional staging (stage 1, <= 5 cells/mu l CSF, n = 42; stage 2, >= 20 cells/mu...

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