Cholera
New Cholera Study Findings Recently Were Published by Researchers at Harvard University School of Medicine
Published in Malaria Weekly, August 22nd, 2011
2011 AUG 22 -- Data detailed in "A systems biology approach to modeling vibrio cholerae gene expression under virulence-inducing conditions" have been presented. "Vibrio cholerae is a Gram-negative bacillus that is the causative agent of cholera. Pathogenesis in vivo occurs through a series of spatiotemporally controlled events under the control of a gene cascade termed the ToxR regulon," investigators in Boston, Massachusetts report.
"Major genes in the ToxR regulon include the master regulators toxRS and tcpPH, the downstream regulator toxT, and virulence factors, the ctxAB and tcpA operons. Our current understanding of the dynamics of virulence...
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Source: Malaria Weekly (2011-08-22)
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