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American University of Beirut

Effective rituximab treatment of B-cell PLL reported

Published in Managed Care Business Week, June 22nd, 2004

Effective treatment of B-cell PLL with rituximab has been reported.

Hematologists in Lebanon described "a patient with B-cell prolymphocytic leukemia (PLL) who was treated successfully with the monoclonal anti-CD20 antibody (rituximab)."

"The patient had recurrent infections due to relative neutropenia, secondary to bone marrow infiltration," noted Y.A. Mourad and coauthors at the American University in Beirut. "After treatment with monoclonal anti-CD20 antibodies (rituximab) 375 mg/m2 weekly for 4 weeks, complete remission was obtained."

"It was documented by normalization of peripheral blood counts, disappearance of...

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