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The Scripps Research Institute

Stem cells placed mice promising for retinal degeneration diseases

Published in Managed Care Business Week, October 12th, 2004

A team of researchers from The Scripps Research Institute was able to preserve visual function in mice that were genetically predisposed to developing a profound degenerative disease that destroys their retinas.

The team injected adult bone marrow-derived stem cells from mice or humans into the back of mouse eyes at an appropriate stage of development and these injections dramatically curtailed retinal degeneration. In the published article, the team shows that the treated eyes of the mice, when compared to the fellow untreated eyes, had a completely normal retinal vasculature, had significantly improved retinal tissue, and responded to light.

"The...

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