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U.S. National Cancer Institute

ART drugs pose potential cancer hazard to exposed children

Published in Managed Care Business Week, November 9th, 2004

According to recent research from the United States, "The current worldwide spread of the human immunodeficiency virus-1 (HIV-1) to the heterosexual population has resulted in approximately 800,000 children born yearly to HIV-1 infected mothers.

"In the absence of antiretroviral intervention, about 25% of the approximately 7,000 children born yearly to HIV-1 infected women in the United States are HIV-1 infected. Administration of zidovudine (AZT) prophylaxis during pregnancy reduces the rate of infant HIV-1 infection to approximately 7%, and further reductions are achieved with the addition of lamivudine (3TC) in the clinical formulation Combivir," reported M.C....

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