Papworth Hospital NHS Trust, Cambridge
Angiogenesis supports intimal proliferation after coronary artery grafting
Published in Managed Care Business Week, July 12th, 2005
According to recent research published in the Journal of Heart and Lung Transplantation, "vascular remodeling is central to the development of transplant coronary artery vasculopathy (CAV). For remodeling to occur, a sustained blood and nutrient supply is essential."
"Here we report on the presence of angiogenesis within the neointima of coronary arteries from cardiac transplant recipients. Coronary arteries from 57 cardiac transplant recipients with CAV were analyzed. Immunocytochemistry with antibodies raised against endothelial cells (CD31, CD34, and vWF), vascular...
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