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Institute Biology & Experimental Med, Buenos Aires
Progesterone neuroprotection in spinal cord trauma involves BDNR upregulation
August 16th, 2005
Progesterone neuroprotection in spinal cord trauma involves upregulation of brain-derived neurotrophic factor. According to a recent report from Argentina, "Progesterone (PROG) provides neuroprotection to the injured central and peripheral nervous system. These effects may be due to regulation of myelin synthesis in glial cells and also to direct actions on neuronal function. "Both types of cells express classical intracellular PROG receptors (PR), while neurons additionally express the PROG membrane-binding site called 25-Dx." "In motoneurons from rats with spinal cord injury (SCI), PROG restores to normal the deficient levels of...
Source: Managed Care Business Week (2005-08-16)
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