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Bayer Corporation
P38alpha/beta MAPK acts as molecular switch to activate quiescent satellite cell
August 16th, 2005
P38alpha/beta MAPK acts as a molecular switch to activate the quiescent satellite cell. According to recent research published in the The Journal of Cell Biology, "Somatic stem cells cycle slowly or remain quiescent until required for tissue repair and maintenance. "Upon muscle injury, stem cells that lie between the muscle fiber and basal lamina (satellite cells) are activated, proliferate, and eventually differentiate to repair the damaged muscle." "Satellite cells in healthy muscle are quiescent, do not express MyoD family transcription factors or cell cycle regulatory genes and are insulated from the surrounding...
Source: Managed Care Business Week (2005-08-16)
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