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Managed Care Business Week

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Aphios Corporation



Deal signed with Japanese firms to develop anticancer therapeutic



August 16th, 2005

Aphios Corporation announced that it has entered a research and development collaboration with two Japanese companies, Bio Research Corporation of Yokohama, Yokohama, Japan, and Tokyo Supply, Ltd., Minato, Japan, to develop an orally-bioavailble anticancer therapeutic.

The collaborators plan to develop a water-soluble paclitaxel prodrug. The molecule is a combination of a paclitaxel molecule, the potent anticancer drug, and a sugar molecule that enhances solubility. This molecular combination is not bioactive prior to treatment and is significantly more water-soluble than paclitaxel.

The water-soluble nature of this novel therapeutic allows for oral...


Source: Managed Care Business Week (2005-08-16)

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