Managed Care Business Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Managed Care Business Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Children's Hospital, Los Angeles
Rac3 expression cultivates malignant lymphoblast precursors
August 16th, 2005
Rac3 expression cultivates malignant lymphoblast precursors. "Numerous studies indirectly implicate Rac GTPases in cancer. To investigate if Rac3 contributes to normal or malignant cell function, we generated rac3 null mutants through gene targeting," scientists in the United States report. "These mice were viable, fertile, and lacked an obvious external phenotype. This shows Rac3 function is dispensable for embryonic development. Bcr/Abl is a deregulated tyrosine kinase that causes chronic myelogenous leukemia and Ph-positive acute lymphoblastic leukemia in humans," according to Y.J. Cho and colleagues, Children's Hospital of Los Angeles. ...
Source: Managed Care Business Week (2005-08-16)
|
