Managed Care Business Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Managed Care Business Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Massachusetts General Hospital
In the debate of atherosclerosis and scavenger receptors, who's right?
August 16th, 2005
Atherosclerosis is a result of the deposition and retention of cholesterol and fats in the arteries. It was believed that scavenger receptors, including SR-A and CD36, bound to cholesterol, leading to its uptake, and that this was a necessary event in atherosclerosis pathogenesis. To validate this idea, several laboratories created mice lacking these receptors and most studies showed that the resulting mice had decreased atherosclerosis and fat accumulation. Thus, it became the dominant hypothesis that cholesterol uptake via SR-A and CD36 were pro-atherogenic. A new study by Mason Freeman and colleagues at Massachusetts General Hospital, which...
Source: Managed Care Business Week (2005-08-16)
|
