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Karolinska University Hospital
Intravenous acetaminophen has weak opioid-sparing effect
August 16th, 2005
Intravenous acetaminophen treatment has a weak opioid-sparing effect in coronary artery bypass patients. Anesthesiologists in Sweden conducted a "prospective, randomized study" to determine "if intravenous acetaminophen compared to oral administration reduced the consumption of opioids and their side effects without an increase in pain during the stay in the intensive care unit (ICU)." "Eighty patients with written informed consent undergoing coronary artery bypass grafting with cardiopulmonary bypass" were enrolled, according to P.H. Pettersson and coauthors at Karolinska University Hospital. "Anesthesia was based on propofol and fentanyl combined...
Source: Managed Care Business Week (2005-08-16)
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