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University of Minnesota

Murine and human ES cell hematopoiesis models reviewed

Published in Managed Care Law Weekly, May 2nd, 2004

Hematopoiesis models based on human and murine embryonic stem (ES) cells have been reviewed.

Human ES cells "provide a unique model and an important resource to analyze early hematopoietic development," scientists in the United States explained.

"Other systems to study mammalian hematopoiesis include mouse ES cells, dissection of timed mouse embryos, or use of human postnatal hematopoietic tissue typically isolated from bone marrow or umbilical cord blood," noted D. Chen and colleagues at the University of Minnesota. "All these models have particular strengths and weaknesses.

"The extensive studies on murine hematopoiesis provide...

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