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Managed Care Law Weekly

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Cornell University, New York City



Celastrol has promise as a neuroprotective agent for treatment of PD, HD



October 9th, 2005

Celastrol has promise as a neuroprotective agent for treatment of Parkinson disease (PD) and Huntington disease (HD).

According to recent research published in the Journal of Neurochemistry, "Oxidative stress and inflammation are implicated in neurodegenerative diseases including Parkinson disease (PD) and Huntington disease (HD). Celastrol is a potent anti-inflammatory and antioxidant compound extracted from a perennial creeping plant belonging to the Celastraceae family."

"Celastrol is known to prevent the production of proinflammatory cytokines, inducible nitric oxide synthase, and lipid peroxidation. Mice were treated with celastrol...


Source: Managed Care Law Weekly (2005-10-09)

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