Managed Care Law Weekly
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Institute of Human Genetics Heidelberg
Carnosine protects against diabetic nephropathy
October 9th, 2005
Carnosine is a protective factor in diabetic nephropathy. "The risk of diabetic nephropathy is partially genetically determined. Diabetic nephropathy is linked to a gene locus on chromosome 18q22.3-q23. We aimed to identify the causative gene on chromosome 18 and to study the mechanism by which the product of this gene could be involved in the development of diabetic nephropathy. DNA polymorphisms were determined in 135 case (diabetic nephropathy) and 107 control (diabetes without nephropathy) subjects," an international team of researchers reports. "The effect of carnosine on the production of extracellular matrix components and transforming growth...
Source: Managed Care Law Weekly (2005-10-09)
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