Managed Care Law Weekly
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Eli Lilly & Company
PTH role in Wnt signaling pathway in bone investigated
October 9th, 2005
The effects of parathyroid hormone were investigated for their role in the Wnt signaling pathway in bone. According to recent research from the United States, "The Writ signaling pathway has recently been demonstrated to play an important role in bone cell function. In previous studies using DNA microarray analyses, we observed a change in some of the molecular components of the canonical Wnt pathway namely, frizzled-1 (FZD-1) and axil, in response to continuous parathyroid hormone (PTH) treatment in rats." "In the present study, we further explored other components of the Wnt signaling pathway in rat distal metaphyseal bone in vivo, and rat...
Source: Managed Care Law Weekly (2005-10-09)
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