University of Tokyo, Japan
New neuroscience findings from University of Tokyo, Department of Life Sciences described
Published in Managed Care Law Weekly, November 12th, 2006
Current study results from the report, "Role of PKA and PKC in histamine H1 receptor-mediated activation of catecholamine neurotransmitter synthesis," have been published. According to recent research from the United States, "Activation of the histamine H1 receptor stimulates tyrosine hydroxylase (TH) to increase catecholamine neurotransmitter synthesis in mammalian brain and adrenal tissues. Histamine non-selectively activates both H1-linked phospholipase (PL) C/inositol phosphates (IP)/diacylglycerol (DAG) signaling and adenylyl cyclase (AC)/adenosine 3',5'-cyclic monophosphate (cAMP) signaling, confounding determination of signaling events involved in H(1)-mediated TH...
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