Baylor College of Medicine
Expression library immunization can improve vaccine antigens
Published in Medical Device Business Week, July 21st, 2004
"Genetic immunization is a novel method for vaccination in which DNA is delivered into the host to drive both cellular and humoral immune responses against its protein product. While genetic immunization can be potent, it requires that one have, in hand, a gene that encodes a protective protein antigen. Therefore, for many diseases, one cannot make a genetic vaccine because no protective antigen is known or no gene for this antigen is available," scientists in the United States report.
"This lack of candidate antigens and their genes is a considerable bottleneck in developing new vaccines...
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