DNA Research
Reports summarize DNA research from Massachusetts Institute of Technology, Department of Biology
Published in Medical Device Business Week, February 28th, 2007
Data detailed in "Replication is required for the RecA localization response to DNA damage in Bacillus subtilis" have been presented. According to a study from the United States, "In both prokaryotes and eukaryotes, proteins involved in DNA repair often organize into multicomponent complexes that can be visualized as foci in living cells. We used a RecA-GFP fusion to examine the subcellular cues that direct RecA-GFP to assemble as foci in response to DNA damage."
"We used two different methods to inhibit initiation of DNA replication and determined that DNA replication is required for the cell to establish RecA-GFP foci after exposure to DNA-damaging agents....
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