Adenoma Immunology

Studies from P. Bioulac-Sage et al add new findings in the area of adenoma immunology

Published in Medical Device Business Week, October 10th, 2007

A new study, 'Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry,' is now available. "Hepatocellular adenomas (HCA) with activated beta-catenin present a high risk of malignant transformation. To permit robust routine diagnosis to allow for HCA subtype classification, we searched new useful markers," investigators in France report.

"We analyzed the expression of candidate genes by quantitative reverse transcription polymerase chain reaction QRT-PCR followed by immunohistochemistry to validate their specificity and sensitivity according to hepatocyte nuclear factor 1 alpha (HNF1alpha) and beta-catenin mutations as well as...

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Source: Medical Device Business Week (2007-10-10)

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