Molecular Imaging

Studies from Stanford University, Medical Department provide new data on molecular imaging

Published in Medical Device Business Week, April 9th, 2008

"2'-Deoxy-2'-[F-18]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([F-18]FEAU) is a promising radiolabeled nucleoside designed to monitor Herpes Simplex Virus Type 1 thymidine kinase (HSV1-tk) reporter gene expression with positron emission tomography (PET). However, the challenging radiosynthesis creates problems for being able to provide [F-18]FEAU routinely," scientists in the United States report.

"We have developed a routine method using a commercial GE TRACERlab FX-FN radiosynthesis module with customized equipment to provide [F-18]FEAU. All radiochemical yields are decay corrected to end-of-bombardment and reported as means s +/- SD. Radiofluorination (33 +/- 8%;...

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Source: Medical Device Business Week (2008-04-09)

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