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Atherosclerosis

Merck/Schering-Plough Pharmaceuticals Comments on Results of the ENHANCE Study

Published in Medical Device Business Week, April 16th, 2008

Results of ENHANCE (Ezetimibe aNd simvastatin in Hypercholesterolemia enhANces atherosClerosis rEgression), an imaging trial in 720 patients with heterozygous familial hypercholesterolemia (HeFH), a rare genetic condition that causes very high levels of LDL "bad" cholesterol and greatly increases the risk for premature coronary artery disease, were presented at the 57th annual scientific sessions of the American College of Cardiology and also were published on-line in The New England Journal of Medicine(i).

As previously reported on Jan. 14, 2008, despite the fact that ezetimibe/simvastatin 10/80 mg (VYTORIN(R) *) significantly lowered LDL "bad" cholesterol more than...

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