Proteomics
Research from Rockefeller University yields new data on proteomics
Published in Medical Device Business Week, May 28th, 2008
According to a study from the United States, "Virulence factor production in Staphylococcus aureus is largely under the control of the accessory gene regulator (ago quorum sensing system. There are four agr groups, all of which exhibit bacterial interference: each agr type synthesizes a cyclic autoinducing peptide (AIP) with a distinct sequence that activates its cognate AgrC receptor and inhibits activation of others."
"To better understand inhibitory AIP-AgrC interactions, we aimed to identify the minimal molecular determinants required to inhibit both non-cognate and cognate receptors. This minimization of the AIP pharmacophore also may have therapeutic relevance as...
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