Angiogenesis
New data from Inha University illuminate research in angiogenesis
Published in Medical Device Business Week, May 28th, 2008
"Angiogenesis imaging agents for single photon emission computed tomography ( SPECT) play a role in diagnosing tumor-induced angiogenesis as well as tumor metastasis. We synthesized and evaluated radiolabeled RGD glycopeptides by incorporation of the [Tc-99m(CO)(3)(H2O)(3)](+) center dot Tc-99m labeled glucosamino-D-c(RGDfK) ([Tc-99m]2) was prepared in 90-93% radiochemical yields (decay corrected)," scientists in South Korea report.
"In vitro cell binding assays demonstrated selective binding [Tc-99m]2 to human umbilical vein endothelial ( HUVE) cells, with inhibition of binding to 37.3% of control levels by 10 mc M of cold authentic compounds. In addition, [Tc-99m]2...
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