Depression
Data on depression reported by researchers at University of Paris
Published in Medical Device Business Week, December 17th, 2008
Research findings, 'Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice,' are discussed in a new report. "Antidepressants such as Selective Serotonin Reuptake Inhibitors (SSRI) act as indirect agonists of serotonin (5-HT) receptors. Although these drugs produce a rapid blockade of serotonin transporters (SERTs) in vitro, several weeks of treatment are necessary to observe clinical benefits," investigators in France report.
"This paradox has not been solved yet. Recent studies have identified modifications of intracellular signaling proteins and target genes that could contribute to...
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