Inflammatory Bowel Disease

Study results from Keio University, Medical Department update understanding of inflammatory bowel disease

Published in Medical Device Business Week, December 31st, 2008

"Tetomilast (OPC-6535) was originally developed as a Compound inhibiting superoxide production in neutrophils. Although its mechanism of action is not completely understood, phosphodiesterase type 4 inhibitory function has been postulated," investigators in Tokyo, Japan report.

"The therapeutic effect of PDE4 inhibitors has been reported for chronic inflammatory disorders such as chronic obstructive pulmonary diseases. In this study we aimed to examine whether tetomilast could be a novel drug for inflammatory bowel diseases by further clarifying its antiinflammatory effects. Cytokines from human peripheral blood mononuclear cells were measured by enzyme-linked...

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Source: Medical Device Business Week (2008-12-31)

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