Enzyme Research

Recent findings in enzyme research described by researchers from L'Oreal

Published in Medical Device Business Week, January 7th, 2009

"Heparanase is a heparan sulphate endo-glycosidase which was previously detected in the outer root sheath of murine hair follicles. Heparanase overexpression was reported to improve mouse hair (re)growth," investigators in Clichy, France report.

"In this study, we investigated its involvement in human hair biology. Immunofluorescence detection was used to explore heparanase distribution in both anagen and catagen hair follicles. Heparanase functionality was assessed in in vitro cultured hair follicles, in the presence of a heparanase activity inhibitor. Our results showed that heparanase expression was (i) primarily located in the inner root sheath (IRS) of human hair...

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Source: Medical Device Business Week (2009-01-07)

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