Lichen Planus Genetics
New lichen planus genetics findings from Icelandic Cancer Society described
Published in Medical Device Business Week, October 21st, 2009
Research findings, 'Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders,' are discussed in a new report. "In a previous cross-sectional study, the authors found a higher rate of TP53 mutation in oral lichen planus (OLP) than in hyperkeratosis. By analysing for TP53 mutations in serial samples from patients on long-term follow-up of their oral lesions, it was hoped to determine if these mutations were related to disease progression," researchers in Iceland report.
"Eight patients presenting with lesions diagnosed clinically as oral leukoplakia or lichen planus were followed from 2 to 12 years. Two to five samples of...
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