Children's Hospital, Boston
Increased cholesterol in prostate tumor cell membranes may be linked to cancer
Published in Medical Device Law Weekly, March 7th, 2004
According to recent research published in the Journal of Cellular Biochemistry, "Cholesterol is a neutral lipid that accumulates in liquid-ordered, detergent-resistant membrane domains called lipid rafts. Lipid rafts serve as membrane platforms for signal transduction mechanisms that mediate cell growth, survival, and a variety of other processes relevant to cancer."
"A number of studies, going back many years, demonstrate that cholesterol accumulates in solid tumors and that cholesterol homeostasis breaks down in the Prostate...
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