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Critical Therapeutics, Inc.

Company licenses exclusive rights to cinnamylidene-anabaseines compounds

Published in Medical Device Law Weekly, October 10th, 2004

Critical Therapeutics, Inc., (CRTX), a biopharmaceutical company focused on the discovery, development, and commercialization of products for respiratory, inflammatory, and critical care diseases, announced that it has licensed rights to a key patent from the University of Florida.

The company's license to U.S. patent no. 5,977,144 provides exclusive composition-of-matter and method-of-use rights to a family of compounds known as cinnamylidene-anabaseines. These compounds target and stimulate the nicotinic alpha-7 cholinergic receptor. Preclinical studies have demonstrated that the alpha-7 receptor on the macrophage cell plays an important role in regulating the...

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