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Lymphoma Therapy

Reports outline lymphoma therapy research from University of Rochester, James P. Wilmot Cancer Center

Published in Medical Device Law Weekly, March 4th, 2007

Fresh data on lymphoma are presented in the report "B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny." According to recent research from the United States, "The long-term immunologic effects of B cell depletion with rituximab and the characteristics of the reconstituting B cell pool in lymphoma patients are not well defined, despite the widespread usage of this therapy."

"Here we report that during the B cell reconstitution phase a majority of the peripheral blood B cells have an immature transitional phenotype (47.8%±25.2% vs. 4.4%±2.4% for normal controls, p<0.0001), similar to what has been described during...

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