Allergies Genetics
New findings from University Children's Hospital in the area of allergies genetics published
Published in Medical Device Law Weekly, July 22nd, 2007
Fresh data on allergies are presented in the report "Connective tissue growth factor expression is regulated by histamine in lung fibroblasts: potential role of histamine in airway remodeling. In the inflamed lung of allergic asthma, an aberrant injury-repair response is accompanied by structural changes in the airway, known as airway remodeling. TGF-beta and its downstream mediator connective tissue growth factor (CTGF) are playing a key role in these processes, resulting in irreversible airway remodelling," researchers in Wurzburg, Germany report.
"As histamine is a key mediator of allergic reactions, we investigated whether histamine is involved in airway remodeling....
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