Acute Lymphoblastic Leukemia
Research conducted at Children's Cancer Institute has provided new information about acute lymphoblastic leukemia in children
Published in Medical Device Law Weekly, August 19th, 2007
New investigation results, "Relapse in children with acute lymphoblastic leukemia involving selection of a preexisting drug-resistant subclone," are detailed in a study published in Blood. According to a study from Sydney, Australia, "Relapse following remission induction chemotherapy remains a barrier to survival in approximately 20% of children suffering from acute lymphoblastic leukemia (ALL). To investigate the mechanism of relapse, 27 matched diagnosis and relapse ALL samples were analyzed for clonal populations using polymerase chain reaction (PCR)-based detection of multiple antigen receptor gene rearrangements."
"These clonal markers revealed the...
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