Studies from J.H. Schultz et al add new findings in the area of physiology

Researchers detail in "Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle," new data in physiology. According to a study from Hamburg, Germany, "Recent studies showed that the Ca(2+)-independent transient outward current (I (to)) is very small or even not detectable in the porcine left ventricle. We investigated whether an altered molecular expression or function of voltage-dependent potassium channels belonging to the Kv4 sub-family and their ancillary Ca(2+)-binding beta sub-unit KChIP2, which contribute to the major fraction of I (to )in other species, may underlie this lack of a significant I (to) in the porcine left ventricle."

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