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Acid Reflux Disease Therapy

Scientists at University of Wisconsin, Department of Surgery target acid reflux disease therapy

Published in Medical Device Law Weekly, December 16th, 2007

Data detailed in 'Gene expression changes of inflammatory mediators in posterior laryngitis due to laryngopharyngeal reflux and evolution with PPI treatment: a preliminary study' have been presented. "Standard of care in laryngopharyngeal reflux (LPR) is acid suppression therapy. Its treatment efficacy and mechanism of action are not well documented," investigators in the United States report.

"No objective study investigating the molecular patterns of inflammation in LPR or in response to proton pump inhibitor (PPI) treatment has been accomplished. We hypothesized that gene expression levels of mediators of inflammation --interleukin 6 (IL6), interleukin 8 (IL8),...

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