Gene Therapy

Khon Kaen University, Medical Department reports research in gene therapy

Published in Medical Device Law Weekly, February 3rd, 2008

According to recent research from Khon Kaen, Thailand, "Our objective was to reveal whether host immune response in hamster opisthorchiasis post-praziquantel treatment could induce apoptotic cell death in inflammatory cells. We, therefore, investigated apoptosis-related gene expression in hamsters re-infected with Opisthorchis viverrini (OV) and re-treated with praziquantel."

"Hamsters were re-infected with OV metacercariae then re-treated with praziquantel. The expression of apoptosis-related genes (i.e. apoptosis gene Bcl-2 associated protein X [BAX], caspase 9, p53 and protein kinase B [PKB]) was detected by real-time reverse transcription-polymerase chain reaction....

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Source: Medical Device Law Weekly (2008-02-03)

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