Monoclonal Antibodies

University of Lubeck details research in monoclonal antibodies

Published in Medical Device Law Weekly, November 23rd, 2008

In this recent report, researchers in Lubeck, Germany conducted a study "To investigate the vitreous levels of bevacizumab and vascular endothelial growth factor-A (VEGF-A) after intravitreal injection of the drug in patients with choroidal neovascularization (CNV). Interventional case series."

"Eleven eyes of 11 patients with submacular hemorrhage and CNV due to age-related macular degeneration (n = 10) or angioid streaks (n = 1). All patients were treatment naive except for a single dose of intravitreal injection of bevacizumab (1.25 mg/50 mu L dose) and subsequent vitrectomy after various intervals (1-101 days) because of active and progressive lesion. Intravitreal...

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Source: Medical Device Law Weekly (2008-11-23)

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