Published in Medical Device Law Weekly, September 27th, 2009
"We have examined the effects of menadione on cellular microtubules ex vivo as well as its binding with purified tubulin and microtubules in vitro. Cell viability experiments using human cervical epithelial cancer cells (HeLa) and human oral epithelial cancer cells (KB) indicated that the IC50 Values for menadione are 25.6 +/- 0.6 and 64.3 +/- 0.36 mc M, respectively,...
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