Spectroscopy
New spectroscopy research from University of Minnesota discussed
Published in Medical Device Law Weekly, September 27th, 2009
"gal-1 (galectin-1) mediates cell-cell and cell-extracellular matrix adhesion, essentially by interacting with beta-galactoside-containing glycans of cell-surface glycoconjugates. Although most structural studies with gal-1 have investigated its binding to simple carbohydrates, in particular lactose and N-acetyl-lactosamine, this view is limited, because gal-1 functions tit the cell surface by interacting with more complex glycans that are heterogeneous in size and composition," scientists writing in the Biochemical Journal report.
"In the present Study we used NMR spectroscopy to investigate the interaction of human gal-1 with a large (120 kDa) complex glycan,...
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