Abdominal Aortic Aneurysm

Research in the area of abdominal aortic aneurysm reported from M.I. Mayranpaa and colleagues

Published in Medical Device Law Weekly, September 27th, 2009

"Mast cells (MCs) are inflammatory cells present in atherosclerotic lesions and neovascularized tissues. Recently, MCs were shown to modulate abdominal aortic aneurysm (AAA) formation in a mouse model," investigators in Helsinki, Finland report.

"Progression of aneurysmatic disease process may also depend on intraluminal thrombus and neovascularization of the aneurysm wall. Here we investigated the relationship between MCs and inflammation, neovascularization, and the presence of intraluminal thrombus in human AAA. Specimens from AAAs and normal control aortas were analyzed with basic histology, immunohistochemical staining, and quantitative real-time polymerase chain...

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Source: Medical Device Law Weekly (2009-09-27)

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