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Thymectomy

Researchers at University of Paris target thymectomy

Published in Medical Device Law Weekly, December 6th, 2009

According to a study from Paris, France, "While the thymus is known to be essential for the initial production of T cells during early life, its contribution to immune development remains a matter of debate. In fact, during cardiac surgery in newborns, the thymus is completely resected to enable better access to the heart to correct congenital heart defects, suggesting that it may be dispensable during childhood and adulthood."

"Here, we show that young adults thymectomized during early childhood exhibit an altered T cell compartment. Specifically, absolute CD4(+) and CD8(+) T cell counts were decreased, and these T cell populations showed substantial loss of naive...

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