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Infectious Disease

Novel mass spectrometry-based test reveals sulfated metabolites

Published in Medical Devices and Surgical Technology Week, March 2nd, 2003

Researchers at the University of California have developed a novel mass spectrometry-based method for studying the metabolic products of mycobacteria and other microorganisms.

"The study of the metabolome presents numerous challenges, first among them being the cataloging of its constituents," according to J.D. Mougous and colleagues. "A step in this direction will be the development of tools to identify metabolites that share common structural features."

"The importance of sulfated molecules in cell-cell communication motivated us to develop a rapid two-step method for identifying these metabolites in microorganisms, particularly in pathogenic...

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