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Breast Cancer

Medullary breast cancers are not an indication for BRCA1 mutation screening

Published in Medical Devices and Surgical Technology Week, May 30th, 2004

Research suggests that medullary breast cancers, independent of family risk factors, are not an indication for BRCA1 mutation screening.

"Recommended guidelines have limited breast cancer gene (BRCA1) mutation testing to individuals with a personal or family history of early onset breast and/or ovarian cancer, and those with multiple affected close relatives. Such large breast cancer families are rare in the general population, limiting the clinical application of the BRCA1 discovery," scientists writing in the journal Breast Cancer Research and Treatment report.

"Previous reports have suggested an association between medullary breast cancer...

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