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Medical Devices and Surgical Technology Week

Susan Hasty, Publisher

Table of Contents . . . June 13th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medical Devices and Surgical Technology Week | Other Publications

Cochlear Implants - Influence of stimulus frequency on neural response telemetry determined

Diagnostics - Novel method enhances peptide and protein extraction from serum

Genomics and Genetics - Optimal conditions for cDNA microarray production determined

Proteomics - Mass spectrometry gas-phase fractionation enhances protein identification

Proteomics - POROS bead-based FACS system facilitates immunoadsorbent development

Acute Coronary Syndromes - Company announces reinitiation of phase IIa trial in ACS

Adrenal Masses - Adrenal masses are often discovered incidentally

Adverse Event - Nationwide recall made of instructions for use of biliary stent

Aesthetic Medicine - New survey reveals dramatic rise in "aging face" surgical procedures

Age-Related Macular Degeneration - Visudyne launched in Japan for treatment of age-related macular degeneration

Allergy Medicine - Diagnosis and treatment of allergy to hymenoptera wasp stings reviewed

Anal Dermatitis - Benign and malignant disorders can be similar to perianal dermatitis

Apoptosis - Cisplatin-induced apoptosis associated with mitochondrial dysregulation

Appointments - Computer aided detection products manufacturer appoints new board members

Artery Closure - Device maker submits PMA for vascular closure system

Asthma - Utility of exhaled NO measurement in asthma monitoring reviewed

Asthma Therapy - Optimal doses of inhaled budesonide determined

Atrial Fibrillation - Atrial fibrillation study commences with Arctic Circler Balloon catheter

Atrial Fibrillation - Lenox Hill Hospital completes less invasive procedures to treat atrial fibrillation

Atrial Fibrillation - Panel recommends continuation of phase III atrial arrhythmia trial

Bioengineering - Artificial cells will pave the way for new treatment modalities

Biotechnology - Quantum dots may facilitate cell research

Birth Control - 100% of Vasclip study patients remain sterile at 2-year follow-up

Bladder Cancer - Elderly patients can tolerate radiotherapy and chemotherapy for bladder cancer

Blood Pressure - Vasotrac DS APM205A blood pressure monitor released

Blood Safety - A new rapid molecular assay detects at least four strains of the SEN virus

Brain Cancer - Synchrotron radiation and platinum extend the survival of rats with glioma

Breast Cancer - Researchers test a nursing intervention outcomes model in breast cancer patients

Breast Cancer - Stereotactic breast biopsy technique is valuable in finding microcalcifications

Broken Legs - Elastic nails help kids with broken legs recover faster

Business & Finance - Diagnostic imaging services provider sells six centers for $10.5M

Business & Finance - Drug delivery company completes strategic reorganization

Business Update - Freedom60 Infusion, Res-Q-Vac Suction Systems distribution agreement announced

Business Update - IFS extends collaboration with pharmaceuticals distributor

Business Update - LASIK and Epi-Lasik distribution, sales, and marketing rights acquired

Business Update - PPD Medical Device launched

Business Update - Sale of SurgiWrap complete; company to receive payments

Business Update - Spacelabs Medical announces $3.1 million order from current customer

Cancer Screening - Inverse PCR-based RFLP scanning detects mutational signatures in human cells

Cancer Therapy - FDA approval granted to investigate new cancer treatment applicator

Cancer Therapy - IMOxine produces immunological activity in those with solid-tumor malignancies

Cancer Therapy - Researcher outlines potentials for using microwaves in medicine

Cancer Therapy - Researchers develop a new animal model of continuous catheterization

Cancer Therapy - Utility of isolated hepatic perfusion reviewed

Cardiac Arrhythmias - FrostByte receives FDA clearance, company poised to launch

Cardiac Resynchronization - Cardiac resynchronization sometimes improves function and quality of life

Cardiac Safety Monitoring - Alliance to offer thorough phase I ECG studies in Europe

Cardiology - Defibrillators reduce risk of sudden cardiac death

Cardiovascular Disease - FDA approves rapid exchange catheter for coronary indications

Cardiovascular Disease - Infusion of n-3 fatty acids attenuates ventricular tachycardia

Cardiovascular Disease - Treatment of internal carotid artery intraluminal thrombus reviewed

Cell Proliferation - Hepatocyte proliferation enhanced by immobilization on 24 nm-sized gold colloid

Cervical Cancer - Clinical testing commences for NMP179 protein cervical cancer screening

Cervical Cancer - DNAwithPap test covered by UnitedHealthcare

Cervical Cancer - Tests of liquid-based cervicovaginal cytology samples yield dynamic results

Chronic Liver Disease - Glycomics analysis yields a noninvasive means of tracking liver cirrhosis

Collaborations - Alliance furthers application of multislice CT technology in cardiology market

Collaborations - Deal signed to develop fusion proteins

Collaborations - Disease management firm signs wound care services agreement

Collaborations - Genomics firm launches kinase sequencing assays

Collaborations - Given enters marketing and sales alliance for new M2A Esophageal Capsule

Collaborations - Second oral drug delivery research deal signed

Colon Cancer - Cyclooxygenase-2 inhibitor helps the cytotoxic effect of chemotherapy drugs

Colon Cancer - Dietary cellulose prevents colon carcinogenesis in rats

Colorectal Cancer - JC virus not linked to genetic instability

Contraception - Modifying vasectomy technique improves effectiveness

Coronary Artery Graft - Diabetic patient reaches 9-month milestone with synthetic graft

Coronary Stents - First full month of U.S. Taxus sales reported

Defibrillation - FDA approves world's thinnest integrated bipolar ICD leads

Dental Care - Laser maker launches cosmetic, soft tissue hygiene dental laser

Dental Implants - $940K grant to fund development of coatings for dental implant longevity

Diabetic Nephropathy - Use of cyclosporine in renal and pancreas transplantation reviewed

Diagnostics - Company reports on test of VScan Tuberculosis test kit

Diagnostics - Flourine-18 FDG PET useful for monitoring Takayasu arteritis

Diagnostics - Helicoblot 2.0 suitable for H. pylori screening in gastric cancer patients

Diagnostics - MRI of the urinary tract can characterize masses and diagnose diseases

Diagnostics - Novel molecular assay useful for detection of influenza A viruses

Diagnostics - Quantitative plasma CMV DNA assay very sensitive

Diagnostics - Rapid urine assay detects benzene metabolites

Diagnostics - Relaxometric properties of paramagnetic pH-responsive liposomes determined

Dialysis - Heparin coating of PVC tubing reduces DEHP exposure

Drug Delivery - Liposomes carrying local anesthetics characterized

Drug Delivery - Optimized microemulsion enables transdermal vinpocetine treatment

Drug Development - Advances in microarray compound screening reviewed

Earwax - New device aids in cerumen removal

Endocrinology - Novel assay identifies estrogenic substances in food

Endocrinology - Novel estrogen receptor binding protein isolated

Endoscopy - FDA issues 510(k) clearance for flexible video-enabled endoscope

Enzymology - Proteolytic imbalance reversed after therapeutic surgery in breast cancer

Expression Analyses - Integrated system launched to improve gene expression analyses for whole blood

Finance - BioArchive product line generates $2.2M in third quarter

Finance - BioSystems business segment demonstrates increasing strength in first quarter

Finance - Biological implant product manufacturer reports financial results

Finance - Biosciences company raises $2.3 million in funding

Finance - Biosurgical device firm reports 18% increase in revenues

Finance - Biotechnology company reports first quarter 2004 financial results

Finance - Canadian biotech company reports loss of $0.09 per share

Finance - Cancer diagnostics company reports financials after merger

Finance - Cancer test maker reports 88.5% increase in revenues

Finance - Cardiac device maker reports 26% increase in sales

Finance - Cardiac diagnostics firm reports 36% increase in revenue of U.S. core business

Finance - Defibrillator maker reports 11% increase in revenue

Finance - Device firm reports revenues of $2.2M

Finance - Device maker reports 76% increase in revenue

Finance - Device maker reports first quarter revenue of $68.2M

Finance - Device maker reports net income of $0.12 per share

Finance - Diabetes management company reports first quarter operating results

Finance - Diagnostic test kit maker reports 15.7% increase in sales

Finance - Diagnostics company reports 8.4% increase in sales

Finance - Diagnostics company reports increased net revenues and first profit

Finance - Diagnostics products company reports first quarter revenues of $1.4 million

Finance - HIV diagnostics company reports 24% increase in revenues

Finance - Hearing company report decreased revenues, increased losses in first quarter

Finance - Hearing technologies company completes $17.2 million financing

Finance - Immunoassay maker reports 15% increase in sales

Finance - Irradiation company reports 42% drop in revenue

Finance - Lens maker reports continued growth in first quarter 2004

Finance - Medical imaging company reports 16% increase in service revenue

Finance - Medical product manufacturer reports second quarter sales increase

Finance - Medical products developer reports first quarter 2004 financial results

Finance - Medical products manufacturer reports increase in second quarter net revenues

Finance - Neonatal-products company's revenues increase 31% over first-quarter 2003

Finance - Ophthalmics company reports first quarter net income of $2.4 million

Finance - Optical instruments manufacturer announces third quarter financial results

Finance - PET equipment maker reports 30% increase in revenue

Finance - Surgical products manufacturer reports 18% increase in sales

Finance - Test kit maker reports 15.8% increase in sales

Gene Expression - Novel binding elements and gene targets for homeodomain protein BARX2 identified

Genomics - Company wins $2.5 million DOE grant for network inference

Genomics - GeneExpress data to support CDER genomics study

Genomics - Lawrence Livermore begins using Phenotype MicroArray

Genomics - NCI purchases Hypercomputer to accelerate genome data research

Genomics and Genetics -  B. subtilis SigD-regulated genes identified by microarray analysis

Genotyping - National Cancer Institute provided with early access to SNP genotyping platform

Gynecological Cancer - Gynecological neoplasms should be assessed with MRI

HIV/AIDS - Company gets representation in three new countries for Rapid HIV Tests

HIV/AIDS - Referral testing agreement signed for HIV phenotypic resistance testing

HIV/AIDS Research - Aldo-keto reductase family pathway generates HP1 from S-1360

Hearing Loss - Progress made in detection of pediatric hearing loss

Heart Failure - Accelerated enrollment expected for RELIANT Trial due to reimbursement proposal

Heart Failure - New cardiac resynchronization therapy defibrillator launched in Europe

Heart Surgery - Polymeric sealant suitable for anastomatic bleeding control

Hematology - Novel gene microarray analysis identifies early B-cell factor targets

Hip Replacement - Commercial total hip replacement systems compared

Hip Replacement - Expression of MMP-13, uPA and PAI-1 does not affect outcome

Imaging Technology - Physicians' perceived risk to fetus from X-rays, CT scans "unrealistically high"

Immunology - Absence of NO production alone does not initiate endothelial cell activation

Immunology - CyA C2 predicts total cholesterol in immunosuppressed kidney transplant patients

Immunology - Roles of TCR and Notch signaling in positive selection clarified

Immunology - TEPA study supports current phase I/II leukemia trial in the U.S.

Immunosuppression - Cyclosporin and tacrolimus have equivalent results in lung transplantation

Immunosuppression - Successful kidney transplants increase with cyclosporine experience

Information Technology - Cancer screening database developed for Maryland public health programs

Information Technology - Device reprocessor unveils customer portal

Kidney Cancer - Study indicates that radiofrequency ablation is 98% effective for small tumors

Kidney Fibrosis - BMP-7 promotes repair of injured kidneys

Knee Replacement - Wichita fusion nail improves knee arthrodesis outcome

Lab Instruments - BD FACSCanto flow cytometry system launched

Lab Instruments - GenePix Autoloader microarray scanner launched

Leukemia - MRI is an important tool in detecting recurrent acute lymphoblastic leukemia

Liver Cancer - Microsphere chemoembolization shows promise

Lung Cancer - Microarray analysis reveals survival-related genes in NSCLC patients

Medical Devices - Dislodged ultrasound lithotripter tip recovered from pulmonary artery

Medical Devices - Health-related quality of life effects of cochlear implants evaluated

Medical Devices - J-tipped guidewire suitable for subclavian artery puncture in RPCS placement

Medical Equipment - Fiftieth Novalis shaped beam surgery system sold

Meningioma - Temozolomide prolongs survival slightly in refractory recurrent meningioma

Menopause - REM sleep disturbed in women with menopausal insomnia

Mergers and Acquisitions - Acquisition creates world's third-largest manufacturer and distributor of breast implants

Mergers and Acquisitions - Acquisition of Quantum Laboratories completed

Mergers and Acquisitions - Companies merge to develop, manufacture, and market medical oncology devices

Mergers and Acquisitions - Device company acquired for $1.5M

Mergers and Acquisitions - MSA to acquire Swedish company

Mergers and Acquisitions - Patterson Dental completes acquisition of sports-medicine distributors

Myelodysplastic Syndrome - Granulocyte DNA models may facilitate MDS diagnosis

Nasolabial Folds - Trial started for hyaluronic acid-based cosmetic tissue augmentation therapy

Neuroscience - DNA microarray analysis helps map hippocampal regions

Neuroscience - Location of P-glycoprotein determined in rat astrocytes

Neurosurgery - ChillerStrip system used for first time during human cerebral aneurysm surgery

Nuclear Medicine - New site-targeted microbubble contrast agents delineate vascular space

Ophthalmology - DTL is suitable alternative to Jet contact lens electrode

Oral Cancer - Radial forearm skin flaps for oral cancer may change histologically

Oral Surgery - Alveolar distraction improves implant placement in narrow ridge

Oral Surgery - Autologous fibrin-platelet glue improves maxillofacial surgery outcome

Oral Surgery - Midazolam effective as sedative for Parkinson disease patients

Oral Surgery - Treatment of cleidocranial dysplasia with osseointegrated implants described

Organ Transplantation - New study may impact viability of liver transplants

Organ Transplants - Cryogenic organ banking getting closer

Orthopedic Surgery - Intramedullary technique effective for broken tibial nail removal

Orthopedics - HHV-6 infection may underlie Langerhans cell histiocytosis

Orthopedics - Most open pediatric forearm fractures have a positive outcome

Otorhinolaryngology - Dental implant-associated peripheral giant cell granuloma described

Ovarian Cancer - Sensitive new indicator developed for diagnosing ovarian malignancy

Pancreatic Islets - Immunosuppression for pancreatic islet transplantation reviewed

Pancreatic Islets - Resistin levels return to normal after islet transplantation

Papillary Thyroid Carcinoma - The MACIS score predicts the outcome of papillary thyroid carcinoma in children

Parkinson's Research - Little Rock cardiologist embarking on Parkinson's research

Patents - Medical company wins patent on methods and devices for mitral valve repair

Patents - Patents granted for blood volume analyzer kit in Canada, Japan

Patents - Patents issued for the new Celsius product line

Patient Care - Electronic hugs-and-kisses system matches newborns to mothers

Patient Safety - Sharps disposal by mail system meets EPA guidelines

Pediatric Health - Cochlear implants work best when started young

Pediatric Health - Engineer helps create world's first artificial heart for children

Personnel - Alan Edrick named executive VP, chief financial officer at biotech firm

Personnel - Biomechanical cardiac replacement developer appoints new board member

Personnel - CEO and President Michael Dale named chairman of device company

Personnel - Healthcare venture capital firm appoints managing director

Personnel - IORT company adds Dr. Michael Friebe to its board of directors

Personnel - John C. Heinmiller promoted to executive VP and CFO of device company

Personnel - Laser maker announces new nomination to board of directors

Personnel - Market intelligence company names vice president, sales

Personnel - Oncology company appoints new general counsel

Pharmaceutical and Drug Development - Novel synthesis of protease inhibitors yield potent anti-HIV activity

Pharmacogenetics - Pharmacogenetics predicted to lead molecular diagnostic segment growth

Photomedicine - Silkworm pheophorbide alpha augments photodynamic therapy in melanoma models

Plastic Surgery - Cytokine neutralization alleviates excess wound fibrosis

Post-Surgical Pain - Data demonstrate single-shot epidural injection provides 48-hour pain relief

Pregnancy - Pregnancy massage may reduce premature births

Premature Ejaculation - Ulysses Desensitizing ring clinically effective for premature ejaculation

Product Licensing - Geron enters telomerase licensing agreement

Prostate Cancer - CPSA test may reduce false diagnoses of prostate cancer, studies show

Prostate Cancer - Dietary alpha-linolenic acid may increase prostate cancer risk

Prostate Cancer - Dietary factors may affect the development of prostate cancer

Prostate Cancer - IsoRay to manufacture Cesium-131 brachytherapy seed through new contract

Prostate Cancer - Researchers describe implementing the prostate cancer prevention trial (PCPT)

Prostate Cancer - Trial tests liposome-encapsulated doxorubicin in advanced prostate cancer

Proteomics - Functional protein chip for in vitro metabolic engineering developed

Proteomics - SAF-1 regulates cell cycle progression through p21 induction

Pulse Oximetry - Pediatric studies report Masimo SET Oximetry as most reliable and accurate

Radiation Oncology - Companies collaborate on DICOM-RT interfaces for oncology-based products

Radiography - Digital and analog radiographs comparable for patients with hip prostheses

Radiotherapy - Company broadens technology base with radioactive liposomes

Reconstructive Surgery - Double transpositional replantation feasible for five-digit amputation

Reconstructive Surgery - Free groin flaps provide skin coverage after tumor resection and trauma

Reconstructive Surgery - Second toe-metatarsal transfer suitable for hypoplastic thumb treatment

Reconstructive Surgery - Topical nitroglycerine improves ischemic flow-through venous flap survival

Reconstructive Surgery - Vascularized fibula bone flap improves intercalary allograft outcome

Reimbursement - New CMS procedure code may apply to E2F Decoy

Renal Cancer - Novel renal cell carcinoma translocation characterized

Respiratory Care - FDA clearance granted to market oxygen therapeutic device

Reversible Obstructive Airway Disease - New Drug Application submitted for Xopenex HFA Metered-Dose Inhaler

Rheumatoid Arthritis - Phase I testing of oral CCR2 antagonist begins

Safety Testing - Cardiovascular safety assessment service launched

Salivary Gland Disorders - Salivary gland function is important in oral and overall health

Schizophrenia - Expression of kynurenine pathway enzyme TDO2 heightened in schizophrenics

Sexual and Reproductive Health - Licensee begins sales of "Ixora for Women"

Sexually Transmitted Diseases - Use of vaginal diaphragm to prevent STDs acceptable to women in study

Short Peripheral Intravenous Devices - StatLock catheter securement devices reduce IV complications in trial

Stem-Cell Research - 3-D analysis of cultured bone useful for continuous monitoring of tissue growth

Stem-Cell Research - Different signaling pathways involved in pathogenesis of CML and EMS

Stem-Cell Research - Endodermal progenitors differentiate into hepatic and pancreatic lineages

Stem-Cell Research - Enhanced stem cell survival associated with specific APC mutations

Stem-Cell Research - Genetic profiling of hair follicle stem cells yields treatment targets

Stem-Cell Research - Greater understanding of ocular stem-cell biology needed

Stem-Cell Research - Improved embryonic stem cell test predicts developmental toxicity

Stem-Cell Research - LIMK1/cofilin-mediated actin reorganization regulates stem cell migration

Stem-Cell Research - Many brainstem neurons express functional MOR or DOR receptors or both

Stem-Cell Research - Novel biomarkers of human pluripotent embryonic carcinoma stem cells identified

Stem-Cell Research - Novel method useful for cell-cell interaction studies and tissue engineering

Stem-Cell Research - Novel neuronal phenotypes generated from neural progenitor cells

Stem-Cell Research - Shock wave-promoted bone formation activates ERK and p38 kinase

Stem-Cell Research - Skin-originated stem cells isolated from pigs

Stem-Cell Research - Soluble Jagged-1 induces hematopoietic stem cell self-renewal

Stem-Cell Research - Stem cells derived via nuclear transplantation regenerates infarcted heart

Stem-Cell Research - c-Kit and nestin expressing cells represent endocrine precursor cells

Stem-Cell Transplantation - Allogeneic stem cell transplant curative in amegakaryocytic thrombocytopenia

Stem-Cell Transplantation - Children recovering from stem-cell transplants suffer diminished resistance

Stem-Cell Transplantation - IFN with very low-dose PBMC infusion induces complete remission in CML relapse

Stem-Cell Transplantation - Pretreatment with hydroxyurea lowers rejection incidence in sickle cell disease

Sudden Cardiac Death - Sudden death can happen even with no structural heart disease

Testicular Cancer - In some cases, conservative surgery for testicular tumors is possible

Thromboembolic Disease - Computed tomography is the main diagnostic tool for DVT and PE

Tissue Engineering - Biodegradable support materials used to produce biphasic cartilage constructs

Tissue Engineering - Inkjet printing used for high-throughput cell patterning

Tissue Engineering - Preincubating tissue engineered constructs enhances donor cell retention

Tissue Engineering - Schwann cells implanted into acellular muscle provides graft for regeneration

Tissue Repair - Quill Barbed Polydioxanone Suture receives CE Marking for dermal closure

Tissue Repair - U.S. patent issued for live biological tissue bonding, welding technology

Tissue Transplantation - Six methods for assessing post-transplant I/R injury compared

Transfusion Medicine - FACS assay suitable for HPA 1a screening

Transplant Medicine - Report: New approach has lung recipients taking far fewer drugs

Trends - Functional genomics enables easy target identification, drives drug discovery

Tumor Marker - Clinical marker CAF-1 distinguishes quiescent from proliferating cells

Vascular Medicine - Graft company adds collagen-coated polyester products to vascular portfolio

Vascular Medicine - Studies: HepaSil shows significant improvement in ePTFE graft patency

Vascular Occlusive Disease - OmniWave Technology granted two U.S. patents

Vascular Procedures - Mariner hydrophilic angiographic catheter launched

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