Susan Hasty, Publisher
Table of Contents . . . June 13th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Devices and Surgical Technology Week | Other Publications
Cochlear Implants - Influence of stimulus frequency on neural response telemetry determined
Diagnostics - Novel method enhances peptide and protein extraction from serum
Genomics and Genetics - Optimal conditions for cDNA microarray production determined
Proteomics - Mass spectrometry gas-phase fractionation enhances protein identification
Proteomics - POROS bead-based FACS system facilitates immunoadsorbent development
Acute Coronary Syndromes - Company announces reinitiation of phase IIa trial in ACS
Adrenal Masses - Adrenal masses are often discovered incidentally
Adverse Event - Nationwide recall made of instructions for use of biliary stent
Aesthetic Medicine - New survey reveals dramatic rise in "aging face" surgical procedures
Age-Related Macular Degeneration - Visudyne launched in Japan for treatment of age-related macular degeneration
Allergy Medicine - Diagnosis and treatment of allergy to hymenoptera wasp stings reviewed
Anal Dermatitis - Benign and malignant disorders can be similar to perianal dermatitis
Apoptosis - Cisplatin-induced apoptosis associated with mitochondrial dysregulation
Appointments - Computer aided detection products manufacturer appoints new board members
Artery Closure - Device maker submits PMA for vascular closure system
Asthma - Utility of exhaled NO measurement in asthma monitoring reviewed
Asthma Therapy - Optimal doses of inhaled budesonide determined
Atrial Fibrillation - Atrial fibrillation study commences with Arctic Circler Balloon catheter
Atrial Fibrillation - Lenox Hill Hospital completes less invasive procedures to treat atrial fibrillation
Atrial Fibrillation - Panel recommends continuation of phase III atrial arrhythmia trial
Bioengineering - Artificial cells will pave the way for new treatment modalities
Biotechnology - Quantum dots may facilitate cell research
Birth Control - 100% of Vasclip study patients remain sterile at 2-year follow-up
Bladder Cancer - Elderly patients can tolerate radiotherapy and chemotherapy for bladder cancer
Blood Pressure - Vasotrac DS APM205A blood pressure monitor released
Blood Safety - A new rapid molecular assay detects at least four strains of the SEN virus
Brain Cancer - Synchrotron radiation and platinum extend the survival of rats with glioma
Breast Cancer - Researchers test a nursing intervention outcomes model in breast cancer patients
Breast Cancer - Stereotactic breast biopsy technique is valuable in finding microcalcifications
Broken Legs - Elastic nails help kids with broken legs recover faster
Business & Finance - Diagnostic imaging services provider sells six centers for $10.5M
Business & Finance - Drug delivery company completes strategic reorganization
Business Update - Freedom60 Infusion, Res-Q-Vac Suction Systems distribution agreement announced
Business Update - IFS extends collaboration with pharmaceuticals distributor
Business Update - LASIK and Epi-Lasik distribution, sales, and marketing rights acquired
Business Update - PPD Medical Device launched
Business Update - Sale of SurgiWrap complete; company to receive payments
Business Update - Spacelabs Medical announces $3.1 million order from current customer
Cancer Screening - Inverse PCR-based RFLP scanning detects mutational signatures in human cells
Cancer Therapy - FDA approval granted to investigate new cancer treatment applicator
Cancer Therapy - IMOxine produces immunological activity in those with solid-tumor malignancies
Cancer Therapy - Researcher outlines potentials for using microwaves in medicine
Cancer Therapy - Researchers develop a new animal model of continuous catheterization
Cancer Therapy - Utility of isolated hepatic perfusion reviewed
Cardiac Arrhythmias - FrostByte receives FDA clearance, company poised to launch
Cardiac Resynchronization - Cardiac resynchronization sometimes improves function and quality of life
Cardiac Safety Monitoring - Alliance to offer thorough phase I ECG studies in Europe
Cardiology - Defibrillators reduce risk of sudden cardiac death
Cardiovascular Disease - FDA approves rapid exchange catheter for coronary indications
Cardiovascular Disease - Infusion of n-3 fatty acids attenuates ventricular tachycardia
Cardiovascular Disease - Treatment of internal carotid artery intraluminal thrombus reviewed
Cell Proliferation - Hepatocyte proliferation enhanced by immobilization on 24 nm-sized gold colloid
Cervical Cancer - Clinical testing commences for NMP179 protein cervical cancer screening
Cervical Cancer - DNAwithPap test covered by UnitedHealthcare
Cervical Cancer - Tests of liquid-based cervicovaginal cytology samples yield dynamic results
Chronic Liver Disease - Glycomics analysis yields a noninvasive means of tracking liver cirrhosis
Collaborations - Alliance furthers application of multislice CT technology in cardiology market
Collaborations - Deal signed to develop fusion proteins
Collaborations - Disease management firm signs wound care services agreement
Collaborations - Genomics firm launches kinase sequencing assays
Collaborations - Given enters marketing and sales alliance for new M2A Esophageal Capsule
Collaborations - Second oral drug delivery research deal signed
Colon Cancer - Cyclooxygenase-2 inhibitor helps the cytotoxic effect of chemotherapy drugs
Colon Cancer - Dietary cellulose prevents colon carcinogenesis in rats
Colorectal Cancer - JC virus not linked to genetic instability
Contraception - Modifying vasectomy technique improves effectiveness
Coronary Artery Graft - Diabetic patient reaches 9-month milestone with synthetic graft
Coronary Stents - First full month of U.S. Taxus sales reported
Defibrillation - FDA approves world's thinnest integrated bipolar ICD leads
Dental Care - Laser maker launches cosmetic, soft tissue hygiene dental laser
Dental Implants - $940K grant to fund development of coatings for dental implant longevity
Diabetic Nephropathy - Use of cyclosporine in renal and pancreas transplantation reviewed
Diagnostics - Company reports on test of VScan Tuberculosis test kit
Diagnostics - Flourine-18 FDG PET useful for monitoring Takayasu arteritis
Diagnostics - Helicoblot 2.0 suitable for H. pylori screening in gastric cancer patients
Diagnostics - MRI of the urinary tract can characterize masses and diagnose diseases
Diagnostics - Novel molecular assay useful for detection of influenza A viruses
Diagnostics - Quantitative plasma CMV DNA assay very sensitive
Diagnostics - Rapid urine assay detects benzene metabolites
Diagnostics - Relaxometric properties of paramagnetic pH-responsive liposomes determined
Dialysis - Heparin coating of PVC tubing reduces DEHP exposure
Drug Delivery - Liposomes carrying local anesthetics characterized
Drug Delivery - Optimized microemulsion enables transdermal vinpocetine treatment
Drug Development - Advances in microarray compound screening reviewed
Earwax - New device aids in cerumen removal
Endocrinology - Novel assay identifies estrogenic substances in food
Endocrinology - Novel estrogen receptor binding protein isolated
Endoscopy - FDA issues 510(k) clearance for flexible video-enabled endoscope
Enzymology - Proteolytic imbalance reversed after therapeutic surgery in breast cancer
Expression Analyses - Integrated system launched to improve gene expression analyses for whole blood
Finance - BioArchive product line generates $2.2M in third quarter
Finance - BioSystems business segment demonstrates increasing strength in first quarter
Finance - Biological implant product manufacturer reports financial results
Finance - Biosciences company raises $2.3 million in funding
Finance - Biosurgical device firm reports 18% increase in revenues
Finance - Biotechnology company reports first quarter 2004 financial results
Finance - Canadian biotech company reports loss of $0.09 per share
Finance - Cancer diagnostics company reports financials after merger
Finance - Cancer test maker reports 88.5% increase in revenues
Finance - Cardiac device maker reports 26% increase in sales
Finance - Cardiac diagnostics firm reports 36% increase in revenue of U.S. core business
Finance - Defibrillator maker reports 11% increase in revenue
Finance - Device firm reports revenues of $2.2M
Finance - Device maker reports 76% increase in revenue
Finance - Device maker reports first quarter revenue of $68.2M
Finance - Device maker reports net income of $0.12 per share
Finance - Diabetes management company reports first quarter operating results
Finance - Diagnostic test kit maker reports 15.7% increase in sales
Finance - Diagnostics company reports 8.4% increase in sales
Finance - Diagnostics company reports increased net revenues and first profit
Finance - Diagnostics products company reports first quarter revenues of $1.4 million
Finance - HIV diagnostics company reports 24% increase in revenues
Finance - Hearing company report decreased revenues, increased losses in first quarter
Finance - Hearing technologies company completes $17.2 million financing
Finance - Immunoassay maker reports 15% increase in sales
Finance - Irradiation company reports 42% drop in revenue
Finance - Lens maker reports continued growth in first quarter 2004
Finance - Medical imaging company reports 16% increase in service revenue
Finance - Medical product manufacturer reports second quarter sales increase
Finance - Medical products developer reports first quarter 2004 financial results
Finance - Medical products manufacturer reports increase in second quarter net revenues
Finance - Neonatal-products company's revenues increase 31% over first-quarter 2003
Finance - Ophthalmics company reports first quarter net income of $2.4 million
Finance - Optical instruments manufacturer announces third quarter financial results
Finance - PET equipment maker reports 30% increase in revenue
Finance - Surgical products manufacturer reports 18% increase in sales
Finance - Test kit maker reports 15.8% increase in sales
Gene Expression - Novel binding elements and gene targets for homeodomain protein BARX2 identified
Genomics - Company wins $2.5 million DOE grant for network inference
Genomics - GeneExpress data to support CDER genomics study
Genomics - Lawrence Livermore begins using Phenotype MicroArray
Genomics - NCI purchases Hypercomputer to accelerate genome data research
Genomics and Genetics - B. subtilis SigD-regulated genes identified by microarray analysis
Genotyping - National Cancer Institute provided with early access to SNP genotyping platform
Gynecological Cancer - Gynecological neoplasms should be assessed with MRI
HIV/AIDS - Company gets representation in three new countries for Rapid HIV Tests
HIV/AIDS - Referral testing agreement signed for HIV phenotypic resistance testing
HIV/AIDS Research - Aldo-keto reductase family pathway generates HP1 from S-1360
Hearing Loss - Progress made in detection of pediatric hearing loss
Heart Failure - Accelerated enrollment expected for RELIANT Trial due to reimbursement proposal
Heart Failure - New cardiac resynchronization therapy defibrillator launched in Europe
Heart Surgery - Polymeric sealant suitable for anastomatic bleeding control
Hematology - Novel gene microarray analysis identifies early B-cell factor targets
Hip Replacement - Commercial total hip replacement systems compared
Hip Replacement - Expression of MMP-13, uPA and PAI-1 does not affect outcome
Imaging Technology - Physicians' perceived risk to fetus from X-rays, CT scans "unrealistically high"
Immunology - Absence of NO production alone does not initiate endothelial cell activation
Immunology - CyA C2 predicts total cholesterol in immunosuppressed kidney transplant patients
Immunology - Roles of TCR and Notch signaling in positive selection clarified
Immunology - TEPA study supports current phase I/II leukemia trial in the U.S.
Immunosuppression - Cyclosporin and tacrolimus have equivalent results in lung transplantation
Immunosuppression - Successful kidney transplants increase with cyclosporine experience
Information Technology - Cancer screening database developed for Maryland public health programs
Information Technology - Device reprocessor unveils customer portal
Kidney Cancer - Study indicates that radiofrequency ablation is 98% effective for small tumors
Kidney Fibrosis - BMP-7 promotes repair of injured kidneys
Knee Replacement - Wichita fusion nail improves knee arthrodesis outcome
Lab Instruments - BD FACSCanto flow cytometry system launched
Lab Instruments - GenePix Autoloader microarray scanner launched
Leukemia - MRI is an important tool in detecting recurrent acute lymphoblastic leukemia
Liver Cancer - Microsphere chemoembolization shows promise
Lung Cancer - Microarray analysis reveals survival-related genes in NSCLC patients
Medical Devices - Dislodged ultrasound lithotripter tip recovered from pulmonary artery
Medical Devices - Health-related quality of life effects of cochlear implants evaluated
Medical Devices - J-tipped guidewire suitable for subclavian artery puncture in RPCS placement
Medical Equipment - Fiftieth Novalis shaped beam surgery system sold
Meningioma - Temozolomide prolongs survival slightly in refractory recurrent meningioma
Menopause - REM sleep disturbed in women with menopausal insomnia
Mergers and Acquisitions - Acquisition creates world's third-largest manufacturer and distributor of breast implants
Mergers and Acquisitions - Acquisition of Quantum Laboratories completed
Mergers and Acquisitions - Companies merge to develop, manufacture, and market medical oncology devices
Mergers and Acquisitions - Device company acquired for $1.5M
Mergers and Acquisitions - MSA to acquire Swedish company
Mergers and Acquisitions - Patterson Dental completes acquisition of sports-medicine distributors
Myelodysplastic Syndrome - Granulocyte DNA models may facilitate MDS diagnosis
Nasolabial Folds - Trial started for hyaluronic acid-based cosmetic tissue augmentation therapy
Neuroscience - DNA microarray analysis helps map hippocampal regions
Neuroscience - Location of P-glycoprotein determined in rat astrocytes
Neurosurgery - ChillerStrip system used for first time during human cerebral aneurysm surgery
Nuclear Medicine - New site-targeted microbubble contrast agents delineate vascular space
Ophthalmology - DTL is suitable alternative to Jet contact lens electrode
Oral Cancer - Radial forearm skin flaps for oral cancer may change histologically
Oral Surgery - Alveolar distraction improves implant placement in narrow ridge
Oral Surgery - Autologous fibrin-platelet glue improves maxillofacial surgery outcome
Oral Surgery - Midazolam effective as sedative for Parkinson disease patients
Oral Surgery - Treatment of cleidocranial dysplasia with osseointegrated implants described
Organ Transplantation - New study may impact viability of liver transplants
Organ Transplants - Cryogenic organ banking getting closer
Orthopedic Surgery - Intramedullary technique effective for broken tibial nail removal
Orthopedics - HHV-6 infection may underlie Langerhans cell histiocytosis
Orthopedics - Most open pediatric forearm fractures have a positive outcome
Otorhinolaryngology - Dental implant-associated peripheral giant cell granuloma described
Ovarian Cancer - Sensitive new indicator developed for diagnosing ovarian malignancy
Pancreatic Islets - Immunosuppression for pancreatic islet transplantation reviewed
Pancreatic Islets - Resistin levels return to normal after islet transplantation
Papillary Thyroid Carcinoma - The MACIS score predicts the outcome of papillary thyroid carcinoma in children
Parkinson's Research - Little Rock cardiologist embarking on Parkinson's research
Patents - Medical company wins patent on methods and devices for mitral valve repair
Patents - Patents granted for blood volume analyzer kit in Canada, Japan
Patents - Patents issued for the new Celsius product line
Patient Care - Electronic hugs-and-kisses system matches newborns to mothers
Patient Safety - Sharps disposal by mail system meets EPA guidelines
Pediatric Health - Cochlear implants work best when started young
Pediatric Health - Engineer helps create world's first artificial heart for children
Personnel - Alan Edrick named executive VP, chief financial officer at biotech firm
Personnel - Biomechanical cardiac replacement developer appoints new board member
Personnel - CEO and President Michael Dale named chairman of device company
Personnel - Healthcare venture capital firm appoints managing director
Personnel - IORT company adds Dr. Michael Friebe to its board of directors
Personnel - John C. Heinmiller promoted to executive VP and CFO of device company
Personnel - Laser maker announces new nomination to board of directors
Personnel - Market intelligence company names vice president, sales
Personnel - Oncology company appoints new general counsel
Pharmaceutical and Drug Development - Novel synthesis of protease inhibitors yield potent anti-HIV activity
Pharmacogenetics - Pharmacogenetics predicted to lead molecular diagnostic segment growth
Photomedicine - Silkworm pheophorbide alpha augments photodynamic therapy in melanoma models
Plastic Surgery - Cytokine neutralization alleviates excess wound fibrosis
Post-Surgical Pain - Data demonstrate single-shot epidural injection provides 48-hour pain relief
Pregnancy - Pregnancy massage may reduce premature births
Premature Ejaculation - Ulysses Desensitizing ring clinically effective for premature ejaculation
Product Licensing - Geron enters telomerase licensing agreement
Prostate Cancer - CPSA test may reduce false diagnoses of prostate cancer, studies show
Prostate Cancer - Dietary alpha-linolenic acid may increase prostate cancer risk
Prostate Cancer - Dietary factors may affect the development of prostate cancer
Prostate Cancer - IsoRay to manufacture Cesium-131 brachytherapy seed through new contract
Prostate Cancer - Researchers describe implementing the prostate cancer prevention trial (PCPT)
Prostate Cancer - Trial tests liposome-encapsulated doxorubicin in advanced prostate cancer
Proteomics - Functional protein chip for in vitro metabolic engineering developed
Proteomics - SAF-1 regulates cell cycle progression through p21 induction
Pulse Oximetry - Pediatric studies report Masimo SET Oximetry as most reliable and accurate
Radiation Oncology - Companies collaborate on DICOM-RT interfaces for oncology-based products
Radiography - Digital and analog radiographs comparable for patients with hip prostheses
Radiotherapy - Company broadens technology base with radioactive liposomes
Reconstructive Surgery - Double transpositional replantation feasible for five-digit amputation
Reconstructive Surgery - Free groin flaps provide skin coverage after tumor resection and trauma
Reconstructive Surgery - Second toe-metatarsal transfer suitable for hypoplastic thumb treatment
Reconstructive Surgery - Topical nitroglycerine improves ischemic flow-through venous flap survival
Reconstructive Surgery - Vascularized fibula bone flap improves intercalary allograft outcome
Reimbursement - New CMS procedure code may apply to E2F Decoy
Renal Cancer - Novel renal cell carcinoma translocation characterized
Respiratory Care - FDA clearance granted to market oxygen therapeutic device
Reversible Obstructive Airway Disease - New Drug Application submitted for Xopenex HFA Metered-Dose Inhaler
Rheumatoid Arthritis - Phase I testing of oral CCR2 antagonist begins
Safety Testing - Cardiovascular safety assessment service launched
Salivary Gland Disorders - Salivary gland function is important in oral and overall health
Schizophrenia - Expression of kynurenine pathway enzyme TDO2 heightened in schizophrenics
Sexual and Reproductive Health - Licensee begins sales of "Ixora for Women"
Sexually Transmitted Diseases - Use of vaginal diaphragm to prevent STDs acceptable to women in study
Short Peripheral Intravenous Devices - StatLock catheter securement devices reduce IV complications in trial
Stem-Cell Research - 3-D analysis of cultured bone useful for continuous monitoring of tissue growth
Stem-Cell Research - Different signaling pathways involved in pathogenesis of CML and EMS
Stem-Cell Research - Endodermal progenitors differentiate into hepatic and pancreatic lineages
Stem-Cell Research - Enhanced stem cell survival associated with specific APC mutations
Stem-Cell Research - Genetic profiling of hair follicle stem cells yields treatment targets
Stem-Cell Research - Greater understanding of ocular stem-cell biology needed
Stem-Cell Research - Improved embryonic stem cell test predicts developmental toxicity
Stem-Cell Research - LIMK1/cofilin-mediated actin reorganization regulates stem cell migration
Stem-Cell Research - Many brainstem neurons express functional MOR or DOR receptors or both
Stem-Cell Research - Novel biomarkers of human pluripotent embryonic carcinoma stem cells identified
Stem-Cell Research - Novel method useful for cell-cell interaction studies and tissue engineering
Stem-Cell Research - Novel neuronal phenotypes generated from neural progenitor cells
Stem-Cell Research - Shock wave-promoted bone formation activates ERK and p38 kinase
Stem-Cell Research - Skin-originated stem cells isolated from pigs
Stem-Cell Research - Soluble Jagged-1 induces hematopoietic stem cell self-renewal
Stem-Cell Research - Stem cells derived via nuclear transplantation regenerates infarcted heart
Stem-Cell Research - c-Kit and nestin expressing cells represent endocrine precursor cells
Stem-Cell Transplantation - Allogeneic stem cell transplant curative in amegakaryocytic thrombocytopenia
Stem-Cell Transplantation - Children recovering from stem-cell transplants suffer diminished resistance
Stem-Cell Transplantation - IFN with very low-dose PBMC infusion induces complete remission in CML relapse
Stem-Cell Transplantation - Pretreatment with hydroxyurea lowers rejection incidence in sickle cell disease
Sudden Cardiac Death - Sudden death can happen even with no structural heart disease
Testicular Cancer - In some cases, conservative surgery for testicular tumors is possible
Thromboembolic Disease - Computed tomography is the main diagnostic tool for DVT and PE
Tissue Engineering - Biodegradable support materials used to produce biphasic cartilage constructs
Tissue Engineering - Inkjet printing used for high-throughput cell patterning
Tissue Engineering - Preincubating tissue engineered constructs enhances donor cell retention
Tissue Engineering - Schwann cells implanted into acellular muscle provides graft for regeneration
Tissue Repair - Quill Barbed Polydioxanone Suture receives CE Marking for dermal closure
Tissue Repair - U.S. patent issued for live biological tissue bonding, welding technology
Tissue Transplantation - Six methods for assessing post-transplant I/R injury compared
Transfusion Medicine - FACS assay suitable for HPA 1a screening
Transplant Medicine - Report: New approach has lung recipients taking far fewer drugs
Trends - Functional genomics enables easy target identification, drives drug discovery
Tumor Marker - Clinical marker CAF-1 distinguishes quiescent from proliferating cells
Vascular Medicine - Graft company adds collagen-coated polyester products to vascular portfolio
Vascular Medicine - Studies: HepaSil shows significant improvement in ePTFE graft patency
Vascular Occlusive Disease - OmniWave Technology granted two U.S. patents
Vascular Procedures - Mariner hydrophilic angiographic catheter launched
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