Susan Hasty, Publisher
Table of Contents . . . June 20th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Devices and Surgical Technology Week | Other Publications
Biotechnology - Encoded microcarriers enable simultaneous analysis of multiple cell types
Diagnostics - Novel method for measuring multiple cytokines from small samples
Diagnostics - Single-cell PCR useful for leptomeningeal B-cell cancer diagnosis
Drug Delivery - Thermal aerosol system enables rapid drug action
Food-Borne Illness - Rapid fluorimetric microplate assay detects seafood toxins
Proteomics - High-throughput assay measures tumor cell S-phase progression
Allergy Medicine - Optimal occlusion time determined for pediatric atopy patch test
Alveolar Soft-Part Sarcoma - Alveolar soft-part sarcoma responsive to intensive chemotherapy
Alzheimer Disease - Neuropathology assessed in mouse model of Alzheimer disease
Anesthesiology - Guidance system can reduce awareness during surgery
Angiology - Renin plus angiotensinogen in renal proximal tubule increases arterial pressure
Animal Models - Silicone balloon catheters facilitate study of visceral pain in animals
Anthrax - Exotoxin components of Bacillus anthracis analyzed by Western blot
Anthrax - Monoclonal antibodies to B. anthracis capsular antigen developed
Antibiotics - Antibiotic-loaded collagen-hyaluronic acid matrix potentially a skin substitute
Apoptosis - Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death
Asthma - CysLT1 receptor expression induces airway responsiveness to leukotriene D-4
Asthma - No link between anti-pneumonia antibodies and asthma
Asthma Therapy - Benzalkonium-induced anaphylaxis reported in nebulizer user
Bacteriology - Protein of Treponema denticola inhibits binding step of collagen phagocytosis
Benign Prostatic Hyperplasia - Cooled ThermoCath catheter provides improved patient comfort in trial
Bioengineering - A novel genetically engineered marker keeps track of stem cells in vivo
Biohazards - Company unveils technology for collection of biohazardous materials
Biotechnology - FRET-based analysis detects subtle change in early cycle-related gene activation
Biotechnology - Impaired myenteric plexus NO production in colitis detected by bioimaging system
Biotechnology - Micromanipulation elucidates forces of actin-based propulsion
Bladder Cancer - Intravesical gemcitabine in superficial bladder cancer is well tolerated
Bladder Volume - Noninvasive pediatric bladder volume device launched
Blood Oxygenation - NIH grant to be used for development of adult brain oxygenation monitor
Bone Marrow Transplantation - Computerized system facilitates drug management
Brain Cancer - Encouraging post-market data reported on GliaSite treatment for brain tumors
Brain Tumors - Interstitial infusion of IL13-PE38QQR into rat brain stem may be future therapy
Brain Tumors - Study reviews molecular targeting for malignant gliomas
Breast Cancer - Breast reduction diminishes breast cancer in high-risk women
Breast Cancer - MR mammography: More sensitive detection, but higher false-positive rates
Breast Cancer - MammoSite boost radiation delivery shows promise in breast cancer study
Breast Cancer - Results from European study show strong RECAF expression by cancer cells
Breast Cancer - Technique helps determine axillary lymph node tumor status in some patients
Breast Cancer - Women with early breast cancer in Australia report needing more support
Burn Medicine - Suction dressings useful for immobilizing dermal substitute
Business & Finance - Safety syringe developer announces record sales
Business Update - AccuSoft Corp. acquires computing software product line
Business Update - Company announces first purchase order for Galileo in U.S.
Business Update - Diagnostics company changes name to Predicant
Business Update - PolyHeme maker added to Nasdaq Biotech Index
Business Update - Technology development company to conduct business under new name
Business Update - Transurgical, Inc., changes company name to reflect core business
Cancer - Altix system helps cancer center accelerate computational disease research
Cancer Metastasis - New methods improve hepatic colorectal metastases resectability
Cancer Metastasis - Tumor-ablative approaches can be used for colorectal liver metastases
Cancer Therapy - Company presents update on TNFerade at Digestive Disease Week
Cancer Therapy - Laryngeal paralysis due to TIVAD catheter tip migration reported
Cancer Therapy - New chemical adaptor unit releases a drug by enzymatic triggering
Cancer Therapy - Simple and sensitive method to measure trabectedin in plasma developed
Cardiac Resynchronization Therapy - New lead delivery tools launched for cardiac resynchronization therapy
Cardiology - Baroreceptor reflex function impaired in mice lacking alpha2A )-adrenoceptors
Cardiology - Causative organisms of infective endocarditis identified
Cardiology - Enzyme activation of the Ca-ATPase may occur through different mechanisms
Cardiology - Myocardial oxygen consumption rate is an index of postischemic recovery
Cardiology - Pacemaker lead endocarditis caused by Achromobacter xylosoxidans reported
Cardiology - Routine IVUS guidance not needed for coronary stent implantation
Cardiovascular Disease - RVOT pacing-defibrillation lead placement safe and effective
Cardiovascular Research - Cardiovascular research now involves proteomics
Cervical Cancer - DNA image cytometry used to diagnose cervical cancer
Cervical Cancer - Long-term outcomes of radiotherapy for cervical cancer reported
Chemotherapy - Mitomycin-C-loaded alginate carriers created for bladder cancer chemotherapy
Chiropractic Care - Technology takes tiny steps in hands-on chiropractic industry
Cholangiocarcinoma - Extended surgical resection improves prognosis of cholangiocarcinoma
Chronic Obstructive Pulmonary Disease - New noninvasive swab test for AAT deficiency offered
Clinical Trial - $1M in study extensions awarded for cardiac safety monitoring and services
Coagulation - Resonance thrombography useful for FDP screening
Collaborations - Deal signed for disease management services for Health Options
Collaborations - Diagnostics firms collaborate to help doctors differentiate allergy-like symptoms
Collaborations - IBM expands alliance to broaden life sciences initiatives
Collaborations - Novartis enters strategic antibody alliance
Collaborations - Partnership signed to offer new custom, standard genotyping products
Collaborations - Partnership to develop in vitro assays using hESC-derived hepatocytes
Collaborations - Pharmaceutical firms collaborate in trial of dermatology product
Collaborations - Service provider relationship deal signed with Fresenius Medical Care
Collaborations - Supply, license agreement signed for catheters
Colon Cancer - Different methods are needed to modifying attributions of colorectal cancer risk
Colonoscopy - Enrollment complete in phase II study of purgative product - INKP-102
Congestive Heart Failure - Research evaluates heart failure treatments for landmark study
Crohn Disease - Data show repeated treatment with Leukine is well tolerated
Crosslinking - Oxidative stress or UV irradiation elevates in situ TGase 2 activity
Cystoscopy - Flexible Cystoscope with Slide-On EndoSheath System launched
Dengue Fever - GRP 78 (BiP) identified as hepatic dengue virus serotype 2 receptor element
Diabetes Management - New Precision Xtra blood glucose test strip launched
Diagnostic Imaging - PET and conventional images of small-cell lung cancers are often discordant
Diagnostic Imaging - Tc-99m-HYNIC annexin-V scans identify primary tumors but miss lymph involvement
Diagnostics - Aminoglycoside array enables high-throughput analysis of RNA interactions
Diagnostics - Coagulation test identifies anti beta2 -glycoprotein I lupus anticoagulants
Diagnostics - Dermatofibrosarcoma protuberans must be distinguished from similar tumors
Diagnostics - Group A rotavirus quantitation by real-time RT-PCR correlates with severity
Diagnostics - Intraoperative liver ultrasound is important for hepatic tumor resection
Diagnostics - MedMira signs Canadian distributor to market Rapid HIV Test Kits
Diagnostics - Novel PCR test detects several fungal pathogens
Diagnostics - Novel immunoassay detects pathogenic E. coli in children
Diagnostics - Novel microarrays detect multple pathogens in serum
Diagnostics - Novel monoclonal antibodies facilitate flow cytometric Toxoplasma detection
Diagnostics - Pv30 antigen suitable for serodiagnosis of malaria in Korea
Diagnostics - Rigorous analysis is essential for classifying breast tissue specimens
Diagnostics - Sandwich dot-ELISA detects S. pneumoniae in CSF
Diagnostics - Semicarbazide and amine slides compared in peptide-protein microarray assay
Diagnostics - ViTALConnect medical diagnostic software tool introduced
Distribution Agreement - Ultrasound scanner company enters distribution relationship with AVS
Drug Delivery - FDA issues 510(k) clearance for eFlow electronic aerosol device
Drug Development - ReceptoPharm completes first step in production of RPI-78M.
Drug Resistance - A. fumigatus variant has decreased susceptibility to multiple antifungals
Ebola Virus - Method for rapid diagnosis of Ebola hemorrhagic fever developed
Emergency Medicine - Triple-contrast CT depicts internal injury from gunshot and stab wounds
Environmental Health - Novel assay provides improved measure of haloacetic acids in drinking water
Enzymology - Anti-GM3 synthase antibody enables immunodetection in human tissue
Epidemiology - High prevalence of H. pylori contact in Argentina
Erectile Dysfunction - Penile prosthesis infection rates decrease with InhibiZone use, study shows
Expression Profiles - New multiplexed reagent introduced for protein, biomarker quantitation
Finance - Anesthetic delivery systems maker announces Q1 increases in domestic sales
Finance - Avitar reports second quarter financial results for fiscal 2004
Finance - Diagnostics company announces third quarter total revenue of $210,521
Finance - Diagnostics company reports improved Q2 and 6-month financial results
Finance - Dialysis services company declares three-for-two stock split
Finance - Digital imaging developer reports increase in revenues
Finance - EPT-focused company closes $10.90 million preferred stock financing
Finance - Electronic instrument makers reports record year-end sales and earnings
Finance - Imaging systems company reports 10% decrease in revenues
Finance - Ion-technology company announces 56% revenue growth for third quarter
Finance - Medical device company reports second quarter financial results
Finance - Medical device manufacturer reports 32% increase in sales
Finance - Medical product manufacturer reports first quarter financial results
Finance - Orthotics company reports net loss
Finance - Pharmaceutical company added to NASDAQ Biotech Index
Finance - Pharmaceutical firm raises $6.4M through sale of common stock
Finance - Stem-cell company awarded $1.3M grant from Israel
Food-Borne Illness - LC-MS/MS method to detect and measure acrylamide in coffee developed
Food-Borne Illness - Rapid method to measure enrofloxacin/ciprofloxacin in milk developed
Gastroenterolgy - Fibrin glue can effectively treat gastrocolonic fistula
Gene Mutation - Mutations in gene encoding filamin B disrupt vertebral segmentation
Genetic Marker - CCR5Delta32 polymorphism a risk factor for ischemic-type biliary lesions
Genetic Screening - A new assay quickly screens families at risk for medullary thyroid cancer
Genome Sequencing - $2.4M NIH grant to be used for picoliter-scale sequencing technology
Genomics - ACAT-1 transcripts predominate in liver and ACAT-2 predominate in the duodenum
Genomics - CRE-II site in SMN promoter positively regulates expression of SMN gene
Genomics - Release of iron from ferritin is an important part of the nicking mechanism
Genomics and Genetics - SrfA-dependent genes identified in Dictyostelium discoideum
Gynecological Cancer - Researchers review spirituality among gynecological cancer patients
Head Trauma - Nerve tissue protein S100 levels identify high-risk patients
Heart Attack - U.S. FDA issues clearance for RAMP Cardiac Marker Test
Heart Disease - Approval sought for human implantation of self-expanding stented heart valve
Heart Disorders - Collaboration to develop 3D image technology for electrophysiologists
Heart Failure - AbioCor implant patient removed from life support due to liver, kidney failure
Heart Failure - Implantable cardioverter defibrillator study results released
Hematological Cancer - Molecular WT1 assay useful for minimal residual disease monitoring
Hemodialysis - Convective-controlled double high flux hemodiafiltration shows promise
Hemodialysis - Tailored schedules may help retain residual renal function
Hepatitis - New preclinical results show prevention of liver injury by histamine
Hip Replacement - Cementless total hip arthroplasty feasible for elderly patients
Hip Replacement - Ultralok uncemented femoral prostheses effective for young patients
Hospital Error - Hospital fined for violations in heart transplant program
Imaging - Fischer Imaging to offer PACS and VIParchive technology
Imaging - Rotating camera puts fresh spin on coronary angiography
Imaging Technology - New mass spectrometry-based tissue imaging technology launched
Immune Suppressant - Everolimus safe and effective immunosuppressant in organ transplantation
Immunnology - Mouse bone marrow contains large numbers of functionally competent neutrophils
Immunology - Epitope-specific sorting method improves scFv characterization
Immunology - Grafted BM only variable associated with increased risk of CMV antigenemia
Immunology - Humanized agonistic anti-human 4-1BB mAb developed
Immunology - Interleukin concentrations vary in peritoneal fluid of women with endometriosis
Immunology - Regulatory role of Blimp-1 clarified
Immunology - Simulect use results in significant reduction in transplant rejection
Immunology - Standardized whole-blood leukocyte function assay validated
Immunology - T cells and macrophages main BAFF-expressing cells in salivary glands from pSS
Immunology - Various immune modulatory molecules induced in CD34+ hematopoietic cells
Implantable Devices - Breakthrough attributes of biothermal battery highlighted
Infection Control - $1.5B annual cost of surgical site infections can be reduced
Inflammatory Bowel Disease - Data presented on two gastrointestinal disease treatments
Information Tech - Clinical data sharing solution available for healthcare providers
Information Technology - Interactive obesity management program introduced
Irritable Bowel Syndrome - IBSTracker launched to study changing IBS marketplace
Ischemic Heart Disease - Coronary perfusion flow is larger in diastolic than systolic arrest in rats
Ischemic Heart Disease - Perioperative beta blocker use is inconsistent in heart disease patients
Ischemic Heart Disease - Urban air pollution may increase the risk of dying in Norway
Kidney Transplantation - Electronic monitoring provides optimal measure of immunosuppression adherence
Knee Replacement - Variables affecting post-TKA range of motion identified
Legal Issues - Inhaled nitric oxide gas and gas delivery devices lawsuit settled
Leukemia - Study looks at marrow stem cells and chemotherapy
Liver Cancer - Proteomics can be useful in researching hepatic diseases
Liver Cancer - Regional chemotherapy for liver tumors appears promising
Liver Cancer - Study reviews modern hepatic imaging
Liver Failure - New scintigraphy test could aid preoperative assessment of liver function
Liver Resection - Laparoscopic liver resection is safe and feasible
Liver Resection - Segmental approach to liver resection reduces intraoperative blood loss
Liver Transplantation - Numerical simulation model of hypothermic machine perfusion effective
Liver Transplants - Positive results reported in comparative Prograf trial
Liver Tumors - Benign liver tumors are found more frequently with abdominal imaging
Liver Tumors - Portal vein embolization can increase the safety of hepatic resection
Market Analysis - Attracting top clinical investigators requires careful planning
Market Analysis - Cardiovascular drugs represent $12.5B exposed to generics
Mass Spectrometry - New protein ID system helps researchers pinpoint more proteins
Medical - Mentor licenses patent covering method for treating urinary incontinence
Medical Devices - Electron holography facilitates study of MTJ microstructure
Melanoma Diagnosis - Proteomic evaluation yields possible uveal melanoma markers
Mergers and Acquisitions - Acquisition offer announced for Profile Therapeutics
Mergers and Acquisitions - Fisher announces expiration of waiting period under Hart-Scott-Rodino
Mergers and Acquisitions - Intermagnetics to acquire maker of RF coils
Mergers and Acquisitions - MediCor announces acquisition of breast implant company
Mergers and Acquisitions - Medical device firm acquired for $2 billion
Mergers and Acquisitions - Medical device supplier acquires medical manufacturing firm
Mergers and Acquisitions - Technology development company acquires Impedance Cardiography technology
Modeling - 3D models being used to determine gene development in heart
Neuroscience - Fluorescent labelling method facilitates 3-D imaging of cochlear tissues
Neuroscience - Microdialysis useful for monitoring cannabinoid influence on cAMP levels
Neuroscience - Novel microelectrode array can isolate individual neurons
Neuroscience - Portable system enables field recordings of primate single neuron activity
Neuroscience - Tissue transglutaminase likely plays important role in neuronal function
Nuclear Medicine - Lobectomy followed by radioiodine manages differential thyroid cancer
Obstetrics - Radioimmunoassay developed to measure 3,3'-T2S in maternal serum
Ophthalmology - Wearable low-vision device gives the sight-impaired a cyber helping hand
Organ Transplants - Registry data demonstrate superior long-term organ transplant outcomes
Orthopedic Surgery - Anterolateral mini-incision total hip replacement reviewed
Orthopedic Surgery - Posterior cruciate-retaining and posterior stabilized TKA compared
Orthopedic Surgery - Posterolateral minimal incision effective for total hip replacement
Orthopedics - Cementless femoral stem bone support compared with novel method
Orthopedics - Synthetic ligament prosthetic effective for recurrent THA dislocation
Orthopedics - Two acetabular cement pressurizers compared
Osteoporosis - New product launched for balloon kyphoplasty
Osteoporosis - Ospemifene effective in reducing bone turnover in postmenopausal women
Otorhinolaryngology - Novel technique improves outcome of laryngeal microsurgery
Ovarian Cancer - Inexperienced surgeons operate on most ovarian cancer patients in Maryland
Ovarian Tumors - Ovarian cystadenofibromas can have malignant features on CT and MRI
Ovarian Tumors - The accuracy of frozen section in diagnosis of ovarian masses is generally good
Pain Medicine - Cold compresses effective for pain relief after total hip replacement
Paralysis - 19-year-old undergoes rare procedure to reverse paralysis
Patents - Broad U.S. patent issued for computational drug design technology
Patents - Patent granted for germicidal device to prevent nosocomial infections
Patents - U.S. issued patent covers emollient-foam technology
Personnel - Allen Andersen named to board of supplement/personal care company
Personnel - CEO Ronald W. Dollens to retire after 32 years at Lilly, spin-off
Personnel - Cardiac diagnostics company announces election of new director
Personnel - Device company reports resignation of chief financial officer
Personnel - Device firm names Ronald L. Greene as VP, sales and marketing
Personnel - Diagnostic imaging services provider announces new chief executive officer
Personnel - Drug discovery supplier hires Charles Powell as VP of sales, marketing
Personnel - E-learning company names Hugh Rienhoff and Thanos Triant to board
Personnel - Gerard E. Puorro and Brian F. Sullivan join board of SonoPrepmaker
Personnel - Japanese life sciences firm names new CEO
Personnel - Jasjit Suri, PhD, becomes director of applied R&D for imaging company
Personnel - Litx company names John Marshall to scientific advisory board
Personnel - Mark Little elected to board; John Tarello retiring
Personnel - Michael Tognotti named director of sales at microarray company
Personnel - New chief executive officer to lead company in spinal implant product launches
Personnel - New president named at diagnostics firm, divestiture announced
Personnel - Patrick Balthrop named CEO of xMap company
Prenatal Testing - Novel technique brings prenatal testing from maternal blood closer to reality
Prognostics - p53 over-expression correlates with local treatment failure in oral carcinoma
Prostate Cancer - Antioxidant system activation is important for prostate cancer patients
Prostate Cancer - Chromosome 16q analysis reveals tumor suppressor gene candidates
Prostate Cancer - Hormonal therapy and radiotherapy improve survival for prostate cancer patients
Prostate Cancer - Quality of life declines in the year before death in men with prostate cancer
Prostate Cancer - Sexual disorders after radical prostatectomy involve the couple
Prostate Cancer - Study finds no connection between prostate cancer and atrazine exposure
Proteomics - CREB binds to multiple loci on chromosome 22
Proteomics - Clinical proteomics is revolutionizing disease detection
Proteomics - Protein secondary structure analyzed by vacuum-UV circular dichroism
Pulmonary - CE Mark approval granted new delivery system for surgical adhesive
Radiology - Dangers of MRI in patients with neurostimulators reviewed
Radiotherapy - Exclusive distribution agreement signed for OneDose surface dosimeter
Renal Disease - Phase I/II trial of E2F Decoy begins for prevention of AV graft failure
Restenosis - Implanted stents with c-myc suppressant engender arterial healing
Saphenous Vein Grafts - Rubicon Filter study in Europe yields positive 30-day follow-up results
Skin Cancer - Retinoid-modulated proteins identified in squamous carcinoma cells
Spine Surgery - Analysis shows non-fusion spine procedure revenues to total $27M in 2005
Staffing - Diagnostics company enters strategic agreement with Physicians On-Call
Stem Cell Research - Cxcr4 receptor may exert trophic influences on precursor cell proliferation
Stem Cell Research - Evidence found for fusion between cardiac and skeletal muscle cells
Stem Cell Research - Self-renewal capacity is a widespread property of neural crest precursor cells
Stem Cell Transplantation - Low-dose alemtuzumab reduces GVHD following myeloablative ASCT
Surgery - NIM-Spine System released; designed to reduce spinal-surgery risk
Surgical Technology - Anterior cervical plate system effective for cervical stabilization
Surgical Technology - NICE guidance has limited effect on procedure performances
Surgical Technology - Painless suction drain removal technique developed
Thyroid Tumors - Cyclin D1 overexpression is significant in thyroid tumors
Tissue Engineering - Crosslinking determines degradation rate and regeneration of acellular tissue
Tissue Engineering - Denatured collagen used as support for FGF-2 delivery system
Transfection - Expression system secretes TAT fusion proteins
Transfusion Medicine - Method developed to measure red blood cell survival following transfusion
Transgenics - Cx36-EGFP associated with AMPA-type glutamate receptor subunit GluR1
Transplantation Medicine - Recovery after HCT for leukemia or lymphoma can take 3-5 years
Ultrasound - Company launches new line of ultrasound probes for the replacement market
Uterine Fibroid Tumors - Effective radiation dose calculated for uterine artery embolization
Wound Care - Innovative "self healing" bandage to help diabetics
Wound Care - V.A.C. GranuFoam Heel Dressing earns APMA seal of approval
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