Susan Hasty, Publisher
Table of Contents . . . June 27th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Medical Devices and Surgical Technology Week | Other Publications
Brain Cancer - Microspheres developed for 5-FU delivery to brain
Breast Cancer - RT-PCR for mammaglobin genes detects sentinel lymph nodes micrometastases
Drug Delivery - Chitosan membrane shows promise for transdermal dosing
Liver Cancer - Novel PCR-array system useful for gene expression profiling
Periodontal Disease - TaqMan PCR assay detects six species of periodontopathic bacteria
Acute Coronary Syndrome - FDA clears new intended uses for Troponin T test
Allergy Medicine - Dermatophagoides atopy patch tests are highly reproducible
Alzheimer Disease - Diffusion tensor imaging detects white matter changes in mouse model
Anemia - Successful cord blood stem cell transplant reported
Angiology - Endovascular management effective for iliac vein occlusive disease
Angiology - Study of decellularized carotid artery vascular grafts released
Anti-Infectives - Polycomplexes of poly(acrylic acid) and streptomycin sulfate characterized
Apoptosis - Labeled Annexin A5 detects programmed cell death in vitro and in vivo
Assisted Reproduction - Medically assisted reproduction still risky in presence of chronic viral disease
Atherosclerosis - PAD patients should be aggressively treated for atherosclerotic risk factors
Atherosclerosis - Vulnerable atherosclerotic plaque identified with novel texaphyrin compounds
Atherosclerotic Disease - Vitamin E in dialysis fluid may reduce endothelial damage
Atrial Fibrillation - Enrollment completed in first stage of atrial fibrillation study
Autoimmune Disease - ELISA for detection of autoantibodies to BP230 developed
Awards - 2004 Analytical Instrumentation Company of the Year named by Frost & Sullivan
Benign Prostatic Hyperplasia - FDA warning letter clarified by biotech firm
Bioengineering - Cell matrix-modified implants stimulate new vessel growth in animals
Biomarker Discovery - Advanced multiplexed protein labeling technology described
Biotechnology - Cytokine flow cytometry assesses cellular immune responses to viral antigens
Biotechnology - Glassy carbon microchip developed for electrospray mass spectrometry
Biotechnology - Microfluidic device enables rapid particle separation
Bladder Prolapse - FDA clears minimally invasive treatment for bladder condition
Bleeding - Application submitted to FDA to market autologous thrombin processing device
Blood Banking - Autologous FG by CryoSeal FS System suggestive for hypothetical blood saving
Blood Screening - Consensus determines principles of screening and prevention of vCJD
Breast Cancer - Breast clinic established in Sri Lanka
Breast Cancer - Concordance between HER-2 testing methods determined
Business & Finance - Biopharmaceutical company reports loss of $0.02 per share
Business & Finance - Device firm announces completion of a $35M series C financing
Business Update - Dow Corning emerges from bankruptcy
Business Update - Genetic manufacturing company relocates
Cancer - First Minnesota hospital to use robot-assisted technology in prostate cancer surgery
Cancer - Scope of breast duct to be distributed in the Middle East
Cancer Diagnostics - S100C staining may aid diagnosis of thyroid lesions
Cancer Research - CEACAM6 crosslinking leads to increased extracellular matrix component adhesion
Cancer Therapy - Electrochemotherapy may be a new treatment for solid tumors
Cancer Therapy - New radiation safety audit program for a research institution is successful
Cancer Therapy - Radiotherapy toxicity linked to abnormal transcriptional responses to DNA damage
Cardiac Monitoring - Housecall Plus remote monitoring system launched
Cardiology - 30-day safety data available for coronary stent
Cardiology - Cardiology imaging and information company to manage stent trial
Cardiology - Cigarette smoking predicts reduced maximal FEV1 level in males but not females
Cardiology - E.U. approves two heart disease treatments
Cardiology - FDA issues marketing clearance for cardiac flat-panel detector
Cardiology - Heparin coating protects blood during open-heart procedures
Cardiology - Intrinsic implantable cardioverter-defibrillator now available in Europe
Cardiology - Medtronic launches InSync cardiac resynchronization therapy system in Japan
Cardiology - New clinical data on stent performance announced
Cardiology - New report shows diagnostics driving cardiovascular market
Cardiology - Recreation of published results may confirm nanobacteria in arteries and valves
Cardiology - Technology company invests in catheter-based technology for heart valve repair
Cardiovascular Disease - Homocysteine added to Poly-Chem analyzer testing menu
Carotid Stenting - CE Mark approval issued for Protege GPS Nitinol Self-Expanding Stent
Cervical Cancer - Optical diagnosis of cervical dysplasia on the horizon
Chirality - Method to determine chirality determination of amino acids developed
Cochlear Implant - Effects of pulse rate on Clarion cochlear implant performance determined
Cochlear Implants - Cochlea is surgically accessible through middle cranial fossa
Collaborations - $1.2M study awarded for cardiac safety monitoring
Collaborations - Cardiac-related software development and license agreement signed
Collaborations - Distribution agreement with ArthroCare completed
Collaborations - License agreement with Celera Diagnostics expanded
Collaborations - Option granted for rights to blood platelet modification technology
Colorectal Cancer - Expression of p185 protein has prognostic value
Coronary Artery Disease - ABT-578-eluting stents may inhibit restenosis
Coronary Artery Disease - Coating and drug-eluting technology licensed for coronary stent system
Coronary Blockage - Diabetic patients benefit from Cypher Sirolimus-eluting coronary stent
Coronavirus - Previously undescribed coronavirus associated with respiratory disease in humans
Critical Care Medicine - Factors predictive of postextubation stridor identified
Critical Care Medicine - Radiologic-assisted endotracheal intubation described
Crosslinking - RPA binds primer-template junction in absence of its major ssDNA-binding domains
Cytomegalovirus - Inverse correlation between CD27 quantitation and cytotoxic effector function
Dengue Fever - IgG avidity test can distinguish primary from secondary dengue infections
Dermatology - Nephrogenic fibrosing dermopathy characterized
Detection - RAPD analysis useful for genotyping clinical Candida spp. isolates
Diabetes Research - New DNA technology used by tissue-banking firm to study diabetes
Diagnostic Imaging - PET may become invaluable for diagnosing and treating brain tumors
Diagnostics - Adaptive mechanical index can shorten color blooming in Doppler flow imaging
Diagnostics - Agreement adds positron emission tomography to medical center's imaging menu
Diagnostics - Automated schistocyte counting method evaluated
Diagnostics - FDA requests and approves new name for infection imaging product
Diagnostics - Flow cytometry is utilized to study natural killer T cells
Diagnostics - Impalpable prostate tumors should be graded T1c regardless of TRUS visibility
Diagnostics - In vivo bioluminescence imaging reveals tumor elements in animal models
Diagnostics - Lab-on-a-chip detects ammonia in human breath
Diagnostics - Metastases may not always come from the primary tumor
Diagnostics - Method to minimize interference of silver staining with MS developed
Diagnostics - Molecular assay detects RSV, influenza, and parainfluenza viruses
Diagnostics - New ClinProt products launched for proteomics, biomarker discovery
Diagnostics - Radioiodinated MMP inhibitor tracers may enhance tumor imaging
Diet and Nutrition - S-adeno-syl-L-methionine in dietary supplements characterized
Disease Diagnostics - New agreement will help develop diagnostic tests in oncology and other diseases
Drug Delivery - Behavior of drug-loaded "microballoons" in stomach characterized
Drug Delivery - Biodegradable thermoplastic depot maintains camptothecin stability
Drug Delivery - Crystallization of NEA in transdermal patch characterized
Drug Delivery - Gel-entrapped tamoxifen offers sustained drug release at tumor sites
Drug Delivery - New drug delivery system allows for combination of drugs
Drug Delivery - Optimal conditions determined for impinging jet-based drug dispersal
Drug Delivery - PLGA microspheres suitable for ocular peptide delivery
Drug Delivery - Patent awarded for new measurement system for pharmaceutical sprays
Drug Delivery - Transdermal Delta8 -THC system developed
Drug Development - Chitosan microspheres potential carrier for drugs
Drug Development - Endotoxin testing not needed for inhalation grade lactose
Drug Safety - Study will use bioinformatics to examine genetic causes of adverse drug reactions
Emphysema - Pivotal trial initiated for new emphysema therapy
Endoscopy - FUSION biliary duct accessories with IDE technology introduced
Erectile Dysfunction - Erectile dysfunction may portend cardiovascular problems
Ewing Sarcoma - Ewing sarcoma of bone metastasizes to the lung
Expression Analysis - Mouse genome microarray launched
Finance - $3.7M Series B financing to advance development of total artificial heart
Finance - $3M private placement to fund Oxycyte blood substitute clinical trials
Finance - Bio-filtration company reports 158% increase in revenues
Finance - Biopharmaceutical company announces pricing of IPO
Finance - Biotech company announces pricing of initial public offering
Finance - Device company announces pricing of public offering
Finance - Device company focused on obesity secures $12M
Finance - Device firm reports 8% decrease in sales
Finance - Diagnostic products firm announces $1M private placement
Finance - Endoscopic product manufacturer announces financial results
Finance - Life sciences company delists from Berlin stock exchange
Finance - Medical device company announces fourth quarter results
Finance - Pharmaceutical firm raises $51M in series C financing
Fungal Infection - FDA clears new fungal infection diagnostic test
Gastric Bypass - Seventeen chosen so far for $1 million gastric bypass experiment
Gastroenteritis - Licensing agreement will further research into norovirus treatments
Gastroenteritis - New license agreement for norovirus detection technology
Gastroenterology - Promising therapies available for the treatment of Crohn disease
Gene Delivery - Novel imaging assesses non-viral transfer systems
Genetic Engineering - Stem cell factor gene-modified natural killer cells overwhelm tumor cells
Genomics and Genetics - ChromoViz software graphically maps genomic data onto chromosomes
Genomics and Genetics - Estrogen-related genes identified in murine uterus
Gynecologic Surgery - Development of an adhesion-reducing substance would be helpful
Gynecologic Surgery - Postsurgical fibrosis regulated by programmed death-1 inhibitory pathway
HIV Diagnosis - HIV-1/2 oral fluid rapid tests under development
HIV/AIDS - (+)-Inophyllum B and (+)-calanolide A candidates for anti-HIV therapy
HIV/AIDS - Intracellularly expressed HIV-1 Tat protein inhibits neural cell proliferation
HIV/AIDS Gene Therapy - TAT-pK/DNA complex useful way to package therapeutic genes for cell transduction
Head & Neck Reconstruction - Researchers use an innovative technique for cutting the pectoralis major muscle
Heart Attack - First international shipment made of automated external defibrillators
Heart Disease - Details of pacemaker study indicate efficacy of biomedical technology
Heart Disease - Enrollment in Taxus registry completed
Heart Disease - Mammograms may help predict cardiovascular disease?
Heart Disease - Positive results presented from PISCES stent trial
Heart Disease - StarClose vascular closure system launched
Heart Failure - AbioCor replacement heart implanted in 14th patient
Heart Failure - Illinois man is 10th in U.S. to survive for year or more with heart pump
Heart Failure - Mechanical support pumps can be a bridge to cardiac transplantation
Hematology - Age and packed cell transfusion volume act synergistically to increase mortality
Hematology - Cryoprecipitate-removed plasma is factor IX source for treatment of hemophilia B
Hereditary Angioedema - DX-88 placed on clinical hold pending review
Hip Replacement - Bone cement reduces acetabular cup wear
Human Genome - Genomics company publishes DNA sequence of human chromosome 10
Hysterectomy - Minimally invasive, minilaparotomically-assisted surgical method developed
Imaging - Nanoparticles illuminate brain tumors for days under MRI
Imaging - When blood can't get to brain, special CT scan helps
Imaging Technology - Despite controversy, consumer hype could drive demand for fetal ultrasound
Immunology - $100,000 invested in software modeling systems for inflammatory diseases
Immunology - Modified interferon-beta protein may one day help multiple sclerosis patients
Immunology - Selected peptides functionally represent the Fc-gammaRII-binding part of IgG1
Infectious Disease - Multiplex PCR effective for Salmonella typing
Infectious Disease - Treatment of long-term catheter-related Brevibacterium described
Information Technology - New tool released to improved protein identification
Kidney Failure - Zemplar (Paricalcitol Injection) receives FDA approval for pediatric use
Knee Replacement - CT-guided knee replacement system improves accuracy
Laser Technology - Distribution agreement reached for laser system treatment for enlarged prostate
Legislation - Pharmaceutical company reports higher revenue, earnings
Liver Cancer - Utility of cryotherapy as ablative treatment evaluated
Liver Tumors - Liver transplantation is feasible for neuroendocrine tumors
Lung Cancer - Benefits of screening for lung cancer with CT are not proven
Lung Cancer - Lung screening test may prove useful as first line of lung cancer testing
Lung Transplantation - FDG-PET scan can find post-transplant lymphoproliferative disorder
Lymphoma - Initial bone marrow involvement is infrequent in nasal-type NK/T cell lymphoma
Magnetic Resonance Imaging - MRI can detect primary lung tumors in rodents
Mangement - Biopharmaceutical company names new board director
Medical Devices - Aortic Starr-Edwards ball valve prosthesis replaced after 28 years
Medical Devices - Femoral nerve catheter knotting reported
Medical Devices - Immunoassay for detection of irradiated prawns developed
Medical Devices - TIPS stent-grafts do not prevent liver transplantation
Medullary Thyroid Cancer - A single, small medullary thyroid tumor does not mandate total thyroidectomy
Melanoma - MART1/MelanA stains have high false-positive rate
Meningioma - Study reviews the biology, diagnosis, and treatment of meningiomas
Mergers & Acquisitions - Boston Scientific to acquire Advanced Bionics
Mergers & Acquisitions - Business information provider Medtech Insight acquired
Mergers & Acquisitions - Cardiovascular software company acquired
Mergers & Acquisitions - Dental implant, device firm acquired by orthopedics company
Mergers & Acquisitions - Ophthalmic device firm commences offer to acquire Drew Scientific Group
Microfluidics - New technology introduced to replace liquid chromatography columns
Molecular Diagnostics - Molecular typing techniques are useful for detecting pathogenic fungi
Nanotechnology - International nanotechnology shores up European shareholder base
Neuroscience - Alterations in tau transcripts correlate with sporadic tauopathy neurofilament
Neuroscience - MRI can locate ataxia-inducing lesions in Miller Fisher syndrome patients
Non-Hodgkin Lymphoma - Extranodal non-Hodgkin lymphoma can occur in the sinonasal tract
Obesity Surgery - Minimally invasive surgery for morbid obesity reviewed
Obstetrics - Amniocentesis, CVS tests decline despite increase in number of older mothers
Obstetrics - Study casts doubt on common surgical procedure to reduce premature birth
Ophthamology - Ocular inflammation treatment on file with FDA
Oral Cancer - Synthetic and natural agents can cause apoptosis in oral cancer cells
Orthopedic Surgery - Prevention of deep vein thrombosis reviewed
Orthopedics - New CT-based classification proposed for acetabular fractures
Osteoporosis - Calcaneal quantitative ultrasound useful for assessing fracture risk
Osteoporosis - Calcaneal ultrasound helps identify premenopausal women at risk for bone loss
Osteoporosis - FDA clears DXL Calscan - a new type of bone densitometers
Osteoporosis - Several factors can result in faulty measurement of BMD by DXA
Osteoporosis - Study: WHO definition isn't applicable to multi-site axial transmission QUS
Ovarian Cancer - Chemotherapy after cytoreductive surgery for ovarian cancer beneficial
Pain Medicine - Greek nurses express their knowledge of pain experiences
Pancreatic Adenocarcinoma - Survival after surgery for pancreatic carcinoma averaged less than 6 months
Pancreatic Cancer - CyberKnife radiosurgery provides local tumor control
Patent Litigation - Court rules in favor of surgical device company's patent
Patents - Eight U.S. patents granted for high-speed cell analysis platform
Patents - Second U.S. patent granted for rapid microbe detection
Patents - U.S. patent granted for its Immunogene therapy for cancer
Patient Safety - Minstrel patient lifts recalled
Personnel - Cancer therapy systems manufacturer adds eighth member to board of directors
Personnel - Dale A. Stringfellow joins biotech company's board of directors
Personnel - Medical device company announces appointment of new board chairman
Personnel - Medical product manufacturer announces appointment of new board member
Personnel - Orthobiologics company appoints new board member
Personnel - Pharmaceutical company names three new leaders to U.S. executive team
Personnel - Technology development company names new vice president, sales and marketing
Pharmacokinetics - Time-resolved X-ray data can identify protein intermediate structures
Phenotyping - EBV-transformed B-cell lines used for reference and research in routine lab
Pneumonia - Phase II study results of pulmonary delivery of amikacin presented
Prostate Cancer - Array CGH superior to standard CGH for detection of DNA loss
Prostate Cancer - CHEK2 mutation is linked to increased prostate cancer risk
Prostate Cancer - Choosing hormone therapy for prostate cancer depends on several factors
Prosthodontics - Diagnostic and surgical template for dental implants developed
Prosthodontics - Utility of conversion partial dentures reviewed
Proteomics - Technique enables efficient production of microchip microdialysis membranes
Pulmonary Ossification - Diffuse pulmonary ossification is usually not clinically apparent
Quality Certifications - Medical device manufacturing facilities earn quality certifications
RNA Research - RNA interference-based microarray developed
Radiotoxicity - COMP-Ang1 protects endothelial cells from radiation-induced apoptosis
Respiratory Medicine - Drug-device combo improves efficiency of pediatric inhalation therapy
Robotics Technology - New partnership announced for marketing crystallization systems
Sexual Dysfunction - Funding enables study to improve women's ability to have orgasm
Spinal Cord Gangliogliomas - Surgical outcome is generally favorable for spinal cord gangliogliomas
Stem Cells - Preclinical studies show that stem cells may reverse diabetes in mice
Stem-Cell Research - Activated neural stem cells contribute to stroke-induced neurogenesis
Stem-Cell Research - Allogeneic PBSCT is feasible for children with beta/beta and beta/E
Stem-Cell Research - BMP-2 controls key early commitment step in embryonic stem cell differentiation
Stem-Cell Research - Cord blood stem cells plus fibrin platelet glue used for wound repair
Stem-Cell Research - Dopaminergic neurons generated from embryonic stem cells
Stem-Cell Research - Embryonic stem cells are an alternate marrow donor source
Stem-Cell Research - GAMT deficiency causes biochemical adaptations in brain and skeletal muscle
Stem-Cell Research - Large defect bone reconstruction using BM-derived SSC not proven for non-union
Stem-Cell Research - Mesenchymal stem cells from adult mouse bone marrow isolated and characterized
Stem-Cell Research - Novel DZIP gene expressed in embryonic stem cells and germ cells is identified
Stem-Cell Research - Pluripotent stem cell line expressing the AML1-ETO fusion protein established
Stem-Cell Research - Poly(NiPA-co-AAc) gel may provide optimal chondrocyte propagation 3D environment
Stem-Cell Research - Regenerative response in ischemic brain is restricted by p21(Cip1/waf1)
Stem-Cell Research - Side population cells in human/mouse epidermis lack stem cell characteristics
Stem-Cell Research - Skeletal muscle differentiation potential of adult BM cells may lead to therapy
Stem-Cell Transplantation - Allogeneic hematopoietic stem cell transplant for lymphoma should be selective
Stem-Cell Transplantation - Predictors of outcome identified in patients with metastatic rhabdomyosarcoma
Stroke - Cerebral oximetry associated with lower stroke rate after cardiac surgery
Tissue Engineering - Cartilage tissue regenerated by serum-free cultured chrondrocyte implantation
Tissue Engineering - Endocytosis of nano-environment produced by colloidal lithography by fibroblasts
Tissue Engineering - Nanocolumns produced for cell culture using colloidal lithography
Tissue Engineering - Web-like structured novel sheet promising for custom-shaped bone regeneration
Toxoplasmosis - T. gondii-specific recombinant antigens useful for serodiagnosis
Transgenics - New transgenic system produces bulk protein
Ultrasonography - Ultrasound affects structure and function of proteins of PPSB complex
Urology - The benefits of radical prostatectomy extend beyond cancer control
Vaccines - DNA system to support research on vaccine devlivery
Vascular Disease - HEALING II CE mark clinical trial initiated
Vascular Treatments - Medical device manufacturer receives two FDA marketing clearances
Virology - Human Coronavirus 229E in nasal specimens detected by RT-PCR hybridization assay
Vitiligo - Efficacy of 308-nm xenon-chloride excimer laser clarified
Weight Control - New device used to eat less with smaller bites
Wound Treatment - LAM Pharmaceutical accelerates Central American product launch
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